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Consensus statement on the diagnosis, management, and treatment of angioedema mediated by bradykinin Part II Treatment, follow-up, and special situations Caballero T; Baeza ML; Cabanas R; Campos A; Cimbollek S; Gomez-Traseira C; Gonzalez-Quevedo T; Guilarte M; Jurado-Palomo J; Larco JI; Lopez-Serrano MC; Lopez-Trascasa M; Marcos C; Munoz-Caro JM; Pedrosa M; Prior N; Rubio M; Sala-Cunill AJ Investig Allergol Clin Immunol 2011[]; 21 (6): 422-41; quiz 442-3BACKGROUND: There are no previous Spanish guidelines or consensus statements on bradykinin-induced angioedema. AIM: To draft a consensus statement on the management and treatment of angioedema mediated by bradykinin in light of currently available scientific evidence and the experience of experts. This statement will serve as a guideline to health professionals. METHODS: The consensus was led by the Spanish Study Group on Bradykinin-Induced Angioedema, a working group of the Spanish Society of Allergology and Clinical Immunology. A review was conducted of scientific papers on different types of bradykinin-induced angioedema (hereditary and acquired angioedema due to C1 inhibitor deficiency, hereditary angioedema related to estrogens, angioedema induced by angiotensin-converting enzyme inhibitors). Several discussion meetings were held to reach the consensus. RESULTS: Treatment approaches are discussed, and the consensus reached is described. Specific situations are addressed, namely, pregnancy, contraception, travelling, blood donation, and organ transplantation. CONCLUSIONS: A review of and consensus on treatment of bradykinin-induced angioedema is presented.|*Angioedema/diagnosis/metabolism/therapy[MESH]|Bradykinin/*antagonists & inhibitors/metabolism[MESH]|Humans[MESH]|Prognosis[MESH] |
