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S1P1 bridges mechanotransduction and angiogenesis during vascular development Givens C; Tzima EDev Cell 2012[Sep]; 23 (3): 451-2Mechanisms of stabilization of the vascular plexus and the role of mechanotransduction in this process are not well understood. In this issue of Developmental Cell, Jung et al. (2012) and Gaengel et al. (2012) describe the ligand-sensitive and mechanosensitive functions of an important vascular G protein-coupled receptor, S1P1.� |