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Soft-tissue masses: histologic basis for decreased signal (short T2) on T2-weighted MR images Sundaram M; McGuire MH; Schajowicz FAJR Am J Roentgenol 1987[Jun]; 148 (6): 1247-50Most soft-tissue masses and tumors of various etiologies and histologies have high signal intensity on T2-weighted pulse sequences (long T2). Of 47 soft-tissue masses, seven had a low signal (short T2) on T2-weighted pulse sequences. All seven masses were tumors, and histologic review showed that their composition differed from that of the other 40 lesions with a long T2 in that the seven masses were relatively acellular and had more collagen. The tumors with a short T2 included one malignant and six benign soft-tissue tumors. Malignant fibrous histiocytoma and aggressive fibromatosis showed paradoxical signal intensities in that they showed both long and short T2. All of the tumors with low signal intensity on T2-weighted images had significant fibrous elements and marked hypocellularity. This study suggests that the less commonly encountered short T2 may be seen in both benign and malignant soft-tissue lesions. A part of the explanation for the low signal on T2-weighted sequences appears to be the relative acellularity and abundant collagen of these tumors in comparison with those that have the same histologic diagnoses but show a high signal. The histologic composition of the tumor rather than the histologic diagnosis appears to influence the MR signal on T2-weighted sequences.|*Magnetic Resonance Spectroscopy[MESH]|Collagen[MESH]|Fibroma/diagnosis/pathology[MESH]|Histiocytoma, Benign Fibrous/diagnosis/pathology[MESH]|Humans[MESH]|Neurofibroma/diagnosis/pathology[MESH]|Physical Phenomena[MESH]|Physics[MESH]|Soft Tissue Neoplasms/*diagnosis/pathology[MESH] |
