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Hypertrophic cardiomyopathy Clinical spectrum and treatment Wigle ED; Rakowski H; Kimball BP; Williams WGCirculation 1995[Oct]; 92 (7): 1680-92HCM is a heterogeneous disease genotypically, phenotypically, pathophysiologically, clinically, and therapeutically. In decisions on the management of these patients, it is important to recognize this heterogeneity and to direct therapy at the predominant abnormalities.|*Cardiomyopathy, Hypertrophic/diagnosis/genetics/physiopathology/therapy[MESH]|Adolescent[MESH]|Adrenergic beta-Antagonists/therapeutic use[MESH]|Adult[MESH]|Aged[MESH]|Atrial Fibrillation/etiology[MESH]|Calcium Channel Blockers/therapeutic use[MESH]|Child[MESH]|Female[MESH]|Humans[MESH]|Male[MESH]|Middle Aged[MESH]|Myocardial Contraction/physiology[MESH]|Myocardial Ischemia/physiopathology[MESH]|Pacemaker, Artificial[MESH]|Tachycardia, Ventricular/etiology[MESH]|Ventricular Fibrillation/etiology[MESH]|Ventricular Function, Left/physiology[MESH] |