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Caries-protective factors in saliva Lagerlof F; Oliveby AAdv Dent Res 1994[Jul]; 8 (2): 229-38Saliva influences caries attack mainly by its rate of flow and by its content of fluoride. The salivary flow rate influences to a high degree the rate of oral and salivary clearance of bacterial substrates included in foods and snacks. This influence is site-dependent. The basal salivary fluoride concentration is low, about 1 mumol/L, independent of salivary flow rate, and not influenced by diurnal variation. After an exposure of the oral cavity to fluoride, the increased fluoride level is decreased by a process influenced mainly by the salivary flow rate and the volumes of saliva in the mouth before and after swallowing. Other less important caries-protective factors in saliva include its buffer ability, its content of calcium, inorganic phosphate, pH-increasing substances, and anti-microbial agents.|Cariostatic Agents/*analysis[MESH]|Dental Caries/etiology/*prevention & control[MESH]|Fluorides/pharmacokinetics[MESH]|Humans[MESH]|Saliva/*chemistry/*physiology[MESH]|Salivary Proteins and Peptides/physiology[MESH] |
