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lüll Syringoma: a review of twenty-nine cases Patrizi A; Neri I; Marzaduri S; Varotti E; Passarini BActa Derm Venereol 1998[Nov]; 78 (6): 460-2The purpose of our study was to identify the clinical characteristics, epidemiologic data and histologic features in 29 cases of syringoma with a duration of lesions prior to the observation between 1 and 25 years. Only one patient complained of moderate itching. In two cases the lesion was solitary, in another the papules formed a lichenified plaque. In six patients only the eyelids were involved and in two patients a symmetrical localization on the forearms was observed. The other 18 patients showed generalized syringoma, 16 with an eruptive onset, 6 of which were familial. One of our cases showed lesions mimicking urticaria pigmentosa and two patients were affected by Down's syndrome. In two cases, histopathology showed association between syringoma and a melanocytic naevus and in one patient with a solitary lesion a clear cell syringoma was observed.|Adolescent[MESH]|Adult[MESH]|Aged[MESH]|Child[MESH]|Diagnosis, Differential[MESH]|Down Syndrome/complications[MESH]|Eyelid Neoplasms/pathology[MESH]|Female[MESH]|Follow-Up Studies[MESH]|Forearm/pathology[MESH]|Humans[MESH]|Hyperpigmentation/pathology[MESH]|Lichenoid Eruptions/pathology[MESH]|Male[MESH]|Middle Aged[MESH]|Neoplasms, Multiple Primary/pathology[MESH]|Nevus, Pigmented/pathology[MESH]|Pruritus/pathology[MESH]|Sweat Gland Neoplasms/genetics/*pathology[MESH]|Syringoma/genetics/*pathology[MESH]|Urticaria Pigmentosa/diagnosis[MESH] |