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10.1182/blood-2014-04-571265

http://scihub22266oqcxt.onion/10.1182/blood-2014-04-571265
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C4260362!4260362!25139357
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suck abstract from ncbi


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pmid25139357      Blood 2014 ; 124 (13): 2046-50
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  • A nonsense mutation in IKBKB causes combined immunodeficiency #MMPMID25139357
  • Mousallem T; Yang J; Urban TJ; Wang H; Adeli M; Parrott RE; Roberts JL; Goldstein DB; Buckley RH; Zhong XP
  • Blood 2014[Sep]; 124 (13): 2046-50 PMID25139357show ga
  • A nonsense mutation in IKBKB caused the absence of IKK? and a lack of T- and B-cell activation through their antigen receptors.IKK? is not necessary for development of T or B lymphocytes but is important for their activation and for the development/function of NK cells.
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