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10.1002/jmri.24728

http://scihub22266oqcxt.onion/10.1002/jmri.24728
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C4336235!4336235!25143262
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suck abstract from ncbi


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pmid25143262      J+Magn+Reson+Imaging 2015 ; 41 (6): 1695-700
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  • Artifactual microhemorrhage generated by SWI processing #MMPMID25143262
  • Li N; Wang WT; Pham DL; Butman JA
  • J Magn Reson Imaging 2015[Jun]; 41 (6): 1695-700 PMID25143262show ga
  • Purpose: To report that artifactual microhemorrhages are introduced by the 2D homodyne filtering method of generating susceptibility weighted images (SWI) when open-ended fringelines (OEF) are present in phase data. Materials and Methods: SWI data from 28 traumatic brain injury (TBI) patients was obtained on a 3T clinical Siemens scanner using both the product 3D gradient echo sequence (GRE) with GRAPPA acceleration and an in-house developed segmented echo planar imaging (sEPI) sequence without GRAPPA acceleration. SWI processing included (1) 2D Homodyne method implemented on the scanner console and (2) a 3D Fourier-based phase unwrapping followed by 3D high pass filtering. Original and enhanced magnitude and phase images were carefully reviewed for sites of type III OEFs and microhemorrhages by a neuroradiologist on a PACS workstation. Results: Nineteen of 28 (68%) phase datasets acquired using GRAPPA-accelerated GRE acquisition demonstrated type III OEFs. In SWI images, artifactual microhemorrhages were found on 17 of 19 (89%) cases generated using 2D homodyne processing. Application of a 3D Fourier-based unwrapping method prior HP filtering minimized the appearance of the phase singularities in the enhanced phase, and did not generate microhemorrhage-like artifacts in magnitude images. Conclusion: The 2D homodyne filtering method may introduce artifacts mimicking intracranial microhemorrhages in SWI images when type III OEFs are present in phase images. Such artifacts could lead to overestimation of pathology, e.g. TBI. This work demonstrates that 3D phase unwrapping methods minimize this artifact. However, methods to properly combine of phase across coils are needed to eliminate this artifact.
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