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10.3390/ma7020769 http://scihub22266oqcxt.onion/10.3390/ma7020769 C5453068!5453068!28788487     free     free     free Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28788487.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Materials+(Basel) 2014 ; 7 (2): 769-86 Nephropedia Template TP {{tp|p=28788487|t=2014. Biocompatibility of Coronary Stents |pdf=|usr=}}{{28788487}} gab.com Text Biocompatibility of Coronary Stents JO: Materials (Basel) http://www.kidney.de/pget.php?&tw=1&pmid=28788487 #FOAvip Cardiovascular disease is the dominant cause of mortality in developed countries, with coronary artery disease (CAD) a predominant contributor. The development of stents to treat CAD was a significant innovation, facilitating effective percutaneous coronary revascularization. Coronary stents have evolved from bare metal compositions, to incorporate advances in pharmacological therapy in what are now known as drug eluting stents (DES). Deployment of a stent overcomes some limitations of balloon angioplasty alone, but provides an acute stimulus for thrombus formation and promotes neointimal hyperplasia. First generation DES effectively reduced in-stent restenosis, but profoundly delay healing and are susceptible to late stent thrombosis, leading to significant clinical complications in the long term. This review characterizes the development of coronary stents, detailing the incremental improvements, which aim to attenuate the major clinical complications of thrombosis and restenosis. Despite these enhancements, coronary stents remain fundamentally incompatible with the vasculature, an issue which has largely gone unaddressed. We highlight the latest modifications and research directions that promise to more holistically design coronary implants that are truly biocompatible. Twit Text FOAVip Biocompatibility of Coronary Stents ????Materials (Basel) http://www.kidney.de/pget.php?&tw=1&pmid=28788487 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28788487 #FOAvip English Wikipedia <ref>{{Cite pmid|28788487}}</ref> Biocompatibility of Coronary Stents #MMPMID28788487 Jeewandara TM; Wise SG; Ng MKC Materials (Basel) 2014[Feb]; 7 (2): 769-86 PMID28788487show ga Cardiovascular disease is the dominant cause of mortality in developed countries, with coronary artery disease (CAD) a predominant contributor. The development of stents to treat CAD was a significant innovation, facilitating effective percutaneous coronary revascularization. Coronary stents have evolved from bare metal compositions, to incorporate advances in pharmacological therapy in what are now known as drug eluting stents (DES). Deployment of a stent overcomes some limitations of balloon angioplasty alone, but provides an acute stimulus for thrombus formation and promotes neointimal hyperplasia. First generation DES effectively reduced in-stent restenosis, but profoundly delay healing and are susceptible to late stent thrombosis, leading to significant clinical complications in the long term. This review characterizes the development of coronary stents, detailing the incremental improvements, which aim to attenuate the major clinical complications of thrombosis and restenosis. Despite these enhancements, coronary stents remain fundamentally incompatible with the vasculature, an issue which has largely gone unaddressed. We highlight the latest modifications and research directions that promise to more holistically design coronary implants that are truly biocompatible. äBiocompatibility of Coronary Stents (epmc).pdf DeepDyve Pubget Overpricing