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10.1093/ckj/sfx017 http://scihub22266oqcxt.onion/10.1093/ckj/sfx017 C5466114!5466114!28616207     free     free     free Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28616207.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Clin+Kidney+J 2017 ; 10 (3): 301-4 Nephropedia Template TP {{tp|p=28616207|t=2017. Changes in metformin use in chronic kidney disease |pdf=|usr=}}{{28616207}} gab.com Text Changes in metformin use in chronic kidney disease JO: Clin Kidney J http://www.kidney.de/pget.php?&tw=1&pmid=28616207 #FOAvip Metformin is one of the oldest and most widely prescribed antidiabetic medicines worldwide. It is the only such medicine that has shown a reduction of cardiovascular mortality in diabetes mellitus type 2. Since many diabetic patients have chronic kidney disease, its use is often curtailed by practitioners due to fear of lactic acidosis and the US Food and Drug Administration (FDA) warnings that, until recently, had been in place for decades. Current guidelines, though somewhat vague regarding dosages, clearly pave the way for spreading the use of metformin in patients with lower glomerular filtration rates. These guidelines also suggest moving away from just looking at serum creatinine to create a cut-off. Metformin?s costs are lower, and in many underdeveloped countries this is the only medicine available for poor patients. More widespread use of metformin will further help with health care costs, as well as obesity. It will simplify the use of diabetes mellitus type 2 management with lower incidences of hypoglycemia. With all the mounting evidence, the FDA is finally requiring labeling changes regarding recommendations, to allow the use of metformin in patients with much reduced kidney function. Twit Text FOAVip Changes in metformin use in chronic kidney disease ????Clin Kidney J http://www.kidney.de/pget.php?&tw=1&pmid=28616207 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28616207 #FOAvip English Wikipedia <ref>{{Cite pmid|28616207}}</ref> Changes in metformin use in chronic kidney disease #MMPMID28616207 Imam TH Clin Kidney J 2017[Jun]; 10 (3): 301-4 PMID28616207show ga Metformin is one of the oldest and most widely prescribed antidiabetic medicines worldwide. It is the only such medicine that has shown a reduction of cardiovascular mortality in diabetes mellitus type 2. Since many diabetic patients have chronic kidney disease, its use is often curtailed by practitioners due to fear of lactic acidosis and the US Food and Drug Administration (FDA) warnings that, until recently, had been in place for decades. Current guidelines, though somewhat vague regarding dosages, clearly pave the way for spreading the use of metformin in patients with lower glomerular filtration rates. These guidelines also suggest moving away from just looking at serum creatinine to create a cut-off. Metformin?s costs are lower, and in many underdeveloped countries this is the only medicine available for poor patients. More widespread use of metformin will further help with health care costs, as well as obesity. It will simplify the use of diabetes mellitus type 2 management with lower incidences of hypoglycemia. With all the mounting evidence, the FDA is finally requiring labeling changes regarding recommendations, to allow the use of metformin in patients with much reduced kidney function. äChanges in metformin use in chronic kidney disease (epmc).pdf DeepDyve Pubget Overpricing