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10.1038/nature21049 http://scihub22266oqcxt.onion/10.1038/nature21049 C5378303!5378303!28099413     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28099413&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28099413.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Nature 2017 ; 541 (7638): 488-93 Nephropedia Template TP {{tp|p=28099413|t=2017. Communication between viruses guides lysis-lysogeny decisions |pdf=|usr=}}{{28099413}} gab.com Text Communication between viruses guides lysis-lysogeny decisions JO: Nature http://www.kidney.de/pget.php?&tw=1&pmid=28099413 #FOAvip Temperate viruses can become dormant in their host cells, a process called lysogeny. In every infection, such viruses need to decide between the lytic and the lysogenic cycles, i.e., whether to replicate and lyse their host or to lysogenize and keep the host viable. Here we show that viruses (phages) of the spBeta group use a small-molecule communication system to coordinate lysis-lysogeny decisions. During infection of its Bacillus host cell, the phage produces a 6aa communication peptide that is released to the medium. In subsequent infections, progeny phages measure the concentration of this peptide and lysogenize if the concentration is sufficiently high. We found that different phages encode different versions of the communication peptide, demonstrating a phage-specific peptide communication code for lysogeny decisions. We termed this communication system the ?arbitrium? system, and further show that it is encoded by 3 phage genes: aimP, producing the peptide, aimR, the intracellular peptide receptor, and aimX, a negative regulator of lysogeny. The arbitrium system enables an offspring phage to communicate with its predecessors, i.e., to estimate the amount of recent prior infections and hence decide whether to employ the lytic or lysogenic cycle. Twit Text FOAVip Communication between viruses guides lysis-lysogeny decisions ????Nature http://www.kidney.de/pget.php?&tw=1&pmid=28099413 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28099413 #FOAvip English Wikipedia <ref>{{Cite pmid|28099413}}</ref> Communication between viruses guides lysis-lysogeny decisions #MMPMID28099413 Erez Z; Steinberger-Levy I; Shamir M; Doron S; Stokar-Avihail A; Peleg Y; Melamed S; Leavitt A; Savidor A; Albeck S; Amitai G; Sorek R Nature 2017[Jan]; 541 (7638): 488-93 PMID28099413show ga Temperate viruses can become dormant in their host cells, a process called lysogeny. In every infection, such viruses need to decide between the lytic and the lysogenic cycles, i.e., whether to replicate and lyse their host or to lysogenize and keep the host viable. Here we show that viruses (phages) of the spBeta group use a small-molecule communication system to coordinate lysis-lysogeny decisions. During infection of its Bacillus host cell, the phage produces a 6aa communication peptide that is released to the medium. In subsequent infections, progeny phages measure the concentration of this peptide and lysogenize if the concentration is sufficiently high. We found that different phages encode different versions of the communication peptide, demonstrating a phage-specific peptide communication code for lysogeny decisions. We termed this communication system the ?arbitrium? system, and further show that it is encoded by 3 phage genes: aimP, producing the peptide, aimR, the intracellular peptide receptor, and aimX, a negative regulator of lysogeny. The arbitrium system enables an offspring phage to communicate with its predecessors, i.e., to estimate the amount of recent prior infections and hence decide whether to employ the lytic or lysogenic cycle. äCommunication between viruses guides lysis-lysogeny decisions (epmc).pdf DeepDyve Pubget Overpricing