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10.1016/j.virol.2012.08.022

http://scihub22266oqcxt.onion/10.1016/j.virol.2012.08.022
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C5119483!5119483!23217626
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suck abstract from ncbi


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pmid23217626      Virology 2013 ; 435 (1): 179-86
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  • Cryo-electron tomography of bacterial viruses #MMPMID23217626
  • Guerrero-Ferreira RC; Wright ER
  • Virology 2013[Jan]; 435 (1): 179-86 PMID23217626show ga
  • Bacteriophage particles contain both simple and complex macromolecular assemblages and machines that enable them to regulate the infection process under diverse environmental conditions with a broad range of bacterial hosts. Recent developments in cryo-electron tomography (cryo-ET) make it possible to observe the interactions of bacteriophages with their host cells under native-state conditions at unprecedented resolution and in three-dimensions. This review describes the application of cryo-ET to studies of bacteriophage attachment, genome ejection, assembly and egress. Current topics of investigation and future directions in the field are also discussed.
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