Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1038/ncomms13337 http://scihub22266oqcxt.onion/10.1038/ncomms13337 C5097161!5097161!27808093     free     free     free Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27808093.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Nat+Commun 2016 ; 7 (ä): ä Nephropedia Template TP {{tp|p=27808093|t=2016. DNA looping mediates nucleosome transfer |pdf=|usr=}}{{27808093}} gab.com Text DNA looping mediates nucleosome transfer JO: Nat Commun http://www.kidney.de/pget.php?&tw=1&pmid=27808093 #FOAvip Proper cell function requires preservation of the spatial organization of chromatin modifications. Maintenance of this epigenetic landscape necessitates the transfer of parental nucleosomes to newly replicated DNA, a process that is stringently regulated and intrinsically linked to replication fork dynamics. This creates a formidable setting from which to isolate the central mechanism of transfer. Here we utilized a minimal experimental system to track the fate of a single nucleosome following its displacement, and examined whether DNA mechanics itself, in the absence of any chaperones or assembly factors, may serve as a platform for the transfer process. We found that the nucleosome is passively transferred to available dsDNA as predicted by a simple physical model of DNA loop formation. These results demonstrate a fundamental role for DNA mechanics in mediating nucleosome transfer and preserving epigenetic integrity during replication. Twit Text FOAVip DNA looping mediates nucleosome transfer ????Nat Commun http://www.kidney.de/pget.php?&tw=1&pmid=27808093 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27808093 #FOAvip English Wikipedia <ref>{{Cite pmid|27808093}}</ref> DNA looping mediates nucleosome transfer #MMPMID27808093 Brennan LD; Forties RA; Patel SS; Wang MD Nat Commun 2016[]; 7 (ä): ä PMID27808093show ga Proper cell function requires preservation of the spatial organization of chromatin modifications. Maintenance of this epigenetic landscape necessitates the transfer of parental nucleosomes to newly replicated DNA, a process that is stringently regulated and intrinsically linked to replication fork dynamics. This creates a formidable setting from which to isolate the central mechanism of transfer. Here we utilized a minimal experimental system to track the fate of a single nucleosome following its displacement, and examined whether DNA mechanics itself, in the absence of any chaperones or assembly factors, may serve as a platform for the transfer process. We found that the nucleosome is passively transferred to available dsDNA as predicted by a simple physical model of DNA loop formation. These results demonstrate a fundamental role for DNA mechanics in mediating nucleosome transfer and preserving epigenetic integrity during replication. äDNA looping mediates nucleosome transfer (epmc).pdf DeepDyve Pubget Overpricing