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10.1016/j.aju.2012.11.008

http://scihub22266oqcxt.onion/10.1016/j.aju.2012.11.008
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C4442922!4442922!26579241
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suck abstract from ncbi


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pmid26579241      Arab+J+Urol 2013 ; 11 (1): 27-32
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  • Disorders of sexual differentiation: II Diagnosis and treatment #MMPMID26579241
  • El-Sherbiny M
  • Arab J Urol 2013[Mar]; 11 (1): 27-32 PMID26579241show ga
  • Objectives: To provide a review and summary of recent advances in the diagnosis and management of disorder(s) of sexual differentiation (DSD), an area that has developed over recent years with implications for the management of children with DSD; and to assess the refinements in the surgical techniques used for genital reconstruction. Methods: Recent publications (in the previous 10 years) were identified using PubMed, as were relevant previous studies, using following keywords; ?diagnosis and management?, ?ambiguous genitalia?, ?intersex?, ?disorders of sexual differentiation?, ?genitogram?, ?endocrine assessment?, ?gender assignment?, ?genitoplasty?, and ?urogenital sinus?. The findings were reviewed. Results: Arbitrary criteria have been developed to select patients likely to have DSD. Unnecessary tests, especially those that require anaesthesia or are associated with radiation exposure, should be limited to situations where a specific question needs to be answered. Laparoscopy is an important diagnostic tool in selected patients. The routine use of multidisciplinary diagnostic and expert surgical teams has become standard. Full disclosure of different therapeutic approaches and their timing is recommended. Conclusions: Diagnostic tests should be tailored according to the available information. Parents and/or patients should be made aware of the paucity of well-designed studies, as these conditions are rare. Unnecessary irreversible surgery should be postponed until a multidisciplinary experienced team, with the parents? and or patients? approval, can make a well-judged decision.
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