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10.1016/j.yfrne.2016.09.002 http://scihub22266oqcxt.onion/10.1016/j.yfrne.2016.09.002 C5429819!5429819!27663243     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27663243&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27663243.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Front+Neuroendocrinol 2017 ; 44 (ä): 1-26 Nephropedia Template TP {{tp|p=27663243|t=2017. Epigenetic impacts of endocrine disruptors in the brain? |pdf=|usr=}}{{27663243}} gab.com Text Epigenetic impacts of endocrine disruptors in the brain JO: Front Neuroendocrinol http://www.kidney.de/pget.php?&tw=1&pmid=27663243 #FOAvip The acquisition of reproductive competence is organized and activated by steroid hormones acting upon the hypothalamus during critical windows of development. This review describes the potential role of epigenetic processes, particularly DNA methylation, in the regulation of sexual differentiation of the hypothalamus by hormones. We examine disruption of these processes by endocrine-disrupting chemicals (EDCs) in an age-, sex-, and region-specific manner, focusing on how perinatal EDCs act through epigenetic mechanisms to reprogram DNA methylation and sex steroid hormone receptor expression throughout life. These receptors are necessary for brain sexual differentiation and their altered expression may underlie disrupted reproductive physiology and behavior. Finally, we review the literature on histone modifications and non-coding RNA involvement in brain sexual differentiation and their perturbation by EDCs. By putting these data into a sex and developmental context we conclude that perinatal EDC exposure alters the developmental trajectory of reproductive neuroendocrine systems in a sex-specific manner. Twit Text FOAVip Epigenetic impacts of endocrine disruptors in the brain ????Front Neuroendocrinol http://www.kidney.de/pget.php?&tw=1&pmid=27663243 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27663243 #FOAvip English Wikipedia <ref>{{Cite pmid|27663243}}</ref> Epigenetic impacts of endocrine disruptors in the brain? #MMPMID27663243 Walker DM; Gore AC Front Neuroendocrinol 2017[Jan]; 44 (ä): 1-26 PMID27663243show ga The acquisition of reproductive competence is organized and activated by steroid hormones acting upon the hypothalamus during critical windows of development. This review describes the potential role of epigenetic processes, particularly DNA methylation, in the regulation of sexual differentiation of the hypothalamus by hormones. We examine disruption of these processes by endocrine-disrupting chemicals (EDCs) in an age-, sex-, and region-specific manner, focusing on how perinatal EDCs act through epigenetic mechanisms to reprogram DNA methylation and sex steroid hormone receptor expression throughout life. These receptors are necessary for brain sexual differentiation and their altered expression may underlie disrupted reproductive physiology and behavior. Finally, we review the literature on histone modifications and non-coding RNA involvement in brain sexual differentiation and their perturbation by EDCs. By putting these data into a sex and developmental context we conclude that perinatal EDC exposure alters the developmental trajectory of reproductive neuroendocrine systems in a sex-specific manner. äEpigenetic impacts of endocrine disruptors in the brain? (epmc).pdf DeepDyve Pubget Overpricing