Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1016/j.immuni.2014.09.008 http://scihub22266oqcxt.onion/10.1016/j.immuni.2014.09.008 C4346319!4346319!25367569     free     free     free Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25367569.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Immunity 2014 ; 41 (4): 518-28 Nephropedia Template TP {{tp|p=25367569|t=2014. HIF Transcription Factors, Inflammation, and Immunity |pdf=|usr=}}{{25367569}} gab.com Text HIF Transcription Factors, Inflammation, and Immunity JO: Immunity http://www.kidney.de/pget.php?&tw=1&pmid=25367569 #FOAvip The hypoxic response in cells and tissues is mediated by the family of hypoxia-inducible factor (HIF) transcription factors that play an integral role in the metabolic changes that drive cellular adaptation to low oxygen availability. HIF expression and stabilization in immune cells can be triggered by hypoxia, but also by other factors associated with pathological stress: e.g., inflammation, infectious microorganisms, and cancer. HIF induces a number of aspects of host immune function, from boosting phagocyte microbicidal capacity to driving T cell differentiation and cytotoxic activity. Cellular metabolism is emerging as a key regulator of immunity, and it constitutes another layer of fine-tuned immune control by HIF that can dictate myeloid cell and lymphocyte development, fate, and function. Here we discuss how oxygen sensing in the immune microenvironment shapes immunological response and examine how HIF and the hypoxia pathway control innate and adaptive immunity. Twit Text FOAVip HIF Transcription Factors, Inflammation, and Immunity ????Immunity http://www.kidney.de/pget.php?&tw=1&pmid=25367569 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25367569 #FOAvip English Wikipedia <ref>{{Cite pmid|25367569}}</ref> HIF Transcription Factors, Inflammation, and Immunity #MMPMID25367569 Palazon A; Goldrath A; Nizet V; Johnson RS Immunity 2014[Oct]; 41 (4): 518-28 PMID25367569show ga The hypoxic response in cells and tissues is mediated by the family of hypoxia-inducible factor (HIF) transcription factors that play an integral role in the metabolic changes that drive cellular adaptation to low oxygen availability. HIF expression and stabilization in immune cells can be triggered by hypoxia, but also by other factors associated with pathological stress: e.g., inflammation, infectious microorganisms, and cancer. HIF induces a number of aspects of host immune function, from boosting phagocyte microbicidal capacity to driving T cell differentiation and cytotoxic activity. Cellular metabolism is emerging as a key regulator of immunity, and it constitutes another layer of fine-tuned immune control by HIF that can dictate myeloid cell and lymphocyte development, fate, and function. Here we discuss how oxygen sensing in the immune microenvironment shapes immunological response and examine how HIF and the hypoxia pathway control innate and adaptive immunity. äHIF Transcription Factors, Inflammation, and Immunity (epmc).pdf DeepDyve Pubget Overpricing