Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1073/pnas.1506254112 http://scihub22266oqcxt.onion/10.1073/pnas.1506254112 C4568217!4568217!26283380     free     free     free Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26283380.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Proc+Natl+Acad+Sci+U+S+A 2015 ; 112 (35): 11001-6 Nephropedia Template TP {{tp|p=26283380|t=2015. IRF5 controls both acute and chronic inflammation |pdf=|usr=}}{{26283380}} gab.com Text IRF5 controls both acute and chronic inflammation JO: Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=26283380 #FOAvip Many of the world?s major chronic diseases are driven by inflammation. The most abundant inflammatory cells in these diseases are myeloid cells, such as macrophages and neutrophils. Both cell types show remarkable phenotypic diversity among tissues. Defining molecular factors that control this diversity provides abundant scope for the generation of more specific and effective therapeutics, as the lack of specificity of the current most widely used antiinflammatory approaches, such as glucocorticoids and nonsteroidal antiinflammatory molecules, leads to widespread problems if used long term, even at relatively low doses. In this study we demonstrate that a transcription factor called IFN regulatory factor 5 controls macrophage and neutrophil aspects of inflammation, and thus its blockade might be an effective therapeutic strategy for multiple indications. Twit Text FOAVip IRF5 controls both acute and chronic inflammation ????Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=26283380 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26283380 #FOAvip English Wikipedia <ref>{{Cite pmid|26283380}}</ref> IRF5 controls both acute and chronic inflammation #MMPMID26283380 Weiss M; Byrne AJ; Blazek K; Saliba DG; Pease JE; Perocheau D; Feldmann M; Udalova IA Proc Natl Acad Sci U S A 2015[Sep]; 112 (35): 11001-6 PMID26283380show ga Many of the world?s major chronic diseases are driven by inflammation. The most abundant inflammatory cells in these diseases are myeloid cells, such as macrophages and neutrophils. Both cell types show remarkable phenotypic diversity among tissues. Defining molecular factors that control this diversity provides abundant scope for the generation of more specific and effective therapeutics, as the lack of specificity of the current most widely used antiinflammatory approaches, such as glucocorticoids and nonsteroidal antiinflammatory molecules, leads to widespread problems if used long term, even at relatively low doses. In this study we demonstrate that a transcription factor called IFN regulatory factor 5 controls macrophage and neutrophil aspects of inflammation, and thus its blockade might be an effective therapeutic strategy for multiple indications. äIRF5 controls both acute and chronic inflammation (epmc).pdf DeepDyve Pubget Overpricing