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Iniencephaly: Case Report #MMPMID26167231
Alvis-Miranda HR; Bula-Anichiarico DA; Calderón-Miranda WG; Moscote-Salazar LR
J Pediatr Neurosci 2015[Apr]; 10 (2): 181-4 PMID26167231show ga
The iniencephaly involves a variable defect in the occipital bone, resulting in a large foramen magnum, partial or total absence of the cervical and thoracic vertebrae, accompanied by incomplete closure of arcs and/or vertebral bodies, significant shortening of the spinal column and hyperextension of the malformed cervicothoracic spine; the individual's face is deviated upward, the mandibular skin is directly continuous with anterior thorax due to the absence of neck. Its incidence is about 1:1000?1:2000 births, so this is a pretty rare neural tube defect. We present a case of iniencephaly in association with cardiovascular, spinal cord, and intracranial malformations that ended demonstrating the low survival of patients affected with this condition.