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10.1007/s40620-016-0320-7 http://scihub22266oqcxt.onion/10.1007/s40620-016-0320-7 C5133181!5133181!27245689     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27245689.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       J+Nephrol 2017 ; 30 (2): 187-200 Nephropedia Template TP {{tp|p=27245689|t=2017. MONITORING ALLOIMMUNE RESPONSE IN KIDNEY TRANSPLANTATION |pdf=|usr=}}{{27245689}} gab.com Text MONITORING ALLOIMMUNE RESPONSE IN KIDNEY TRANSPLANTATION JO: J Nephrol http://www.kidney.de/pget.php?&tw=1&pmid=27245689 #FOAvip Currently, immunosuppressive therapy in kidney transplant recipients is generally performed by protocols and adjusted according to functional or histological evaluation of the allograft and/or signs of drug toxicity or infection. As a result, a large fraction of patients are likely to receive too much or too little immunosuppression, exposing them to higher rates of infection, malignancy and drug toxicity, or increased risk of acute and chronic graft injury from rejection, respectively. Developing reliable biomarkers is crucial for individualizing therapy aimed at extending allograft survival. Emerging data indicate that many assays, likely used in panels rather than single assays, have potential to be diagnostic and predictive of short and also long-term outcome.While numerous cross-sectional studies have found associations between the results of these assays and the presence of clinically relevant post-transplantation outcomes, data from prospective studies are still scanty, thereby preventing widespread implementation in the clinic. Of note, some prospective, randomized, multicenter biomarker-driven studies are currently on-going aiming at confirming such preliminary data. These works as well as other future studies are highly warranted to test the hypothesis that tailoring immunosuppression on the basis of results offered by these biomarkers leads to better outcomes than current standard clinical practice. Twit Text FOAVip MONITORING ALLOIMMUNE RESPONSE IN KIDNEY TRANSPLANTATION ????J Nephrol http://www.kidney.de/pget.php?&tw=1&pmid=27245689 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27245689 #FOAvip English Wikipedia <ref>{{Cite pmid|27245689}}</ref> MONITORING ALLOIMMUNE RESPONSE IN KIDNEY TRANSPLANTATION #MMPMID27245689 Bestard O; Cravedi P J Nephrol 2017[Apr]; 30 (2): 187-200 PMID27245689show ga Currently, immunosuppressive therapy in kidney transplant recipients is generally performed by protocols and adjusted according to functional or histological evaluation of the allograft and/or signs of drug toxicity or infection. As a result, a large fraction of patients are likely to receive too much or too little immunosuppression, exposing them to higher rates of infection, malignancy and drug toxicity, or increased risk of acute and chronic graft injury from rejection, respectively. Developing reliable biomarkers is crucial for individualizing therapy aimed at extending allograft survival. Emerging data indicate that many assays, likely used in panels rather than single assays, have potential to be diagnostic and predictive of short and also long-term outcome.While numerous cross-sectional studies have found associations between the results of these assays and the presence of clinically relevant post-transplantation outcomes, data from prospective studies are still scanty, thereby preventing widespread implementation in the clinic. Of note, some prospective, randomized, multicenter biomarker-driven studies are currently on-going aiming at confirming such preliminary data. These works as well as other future studies are highly warranted to test the hypothesis that tailoring immunosuppression on the basis of results offered by these biomarkers leads to better outcomes than current standard clinical practice. äMONITORING ALLOIMMUNE RESPONSE IN KIDNEY TRANSPLANTATION (epmc).pdf DeepDyve Pubget Overpricing