Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1371/journal.pbio.2002711 http://scihub22266oqcxt.onion/10.1371/journal.pbio.2002711 C5501695!5501695!28650960     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28650960.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       PLoS+Biol 2017 ; 15 (6): ä Nephropedia Template TP {{tp|p=28650960|t=2017. Phosphatidylserine externalization, ?necroptotic bodies? release, and phagocytosis during necroptosis |pdf=|usr=}}{{28650960}} gab.com Text Phosphatidylserine externalization, necroptotic bodies release, and phagocytosis during necroptosis JO: PLoS Biol http://www.kidney.de/pget.php?&tw=1&pmid=28650960 #FOAvip Necroptosis is a regulated, nonapoptotic form of cell death initiated by receptor-interacting protein kinase-3 (RIPK3) and mixed lineage kinase domain-like (MLKL) proteins. It is considered to be a form of regulated necrosis, and, by lacking the ?find me? and ?eat me? signals that are a feature of apoptosis, necroptosis is considered to be inflammatory. One such ?eat me? signal observed during apoptosis is the exposure of phosphatidylserine (PS) on the outer plasma membrane. Here, we demonstrate that necroptotic cells also expose PS after phosphorylated mixed lineage kinase-like (pMLKL) translocation to the membrane. Necroptotic cells that expose PS release extracellular vesicles containing proteins and pMLKL to their surroundings. Furthermore, inhibition of pMLKL after PS exposure can reverse the process of necroptosis and restore cell viability. Finally, externalization of PS by necroptotic cells drives recognition and phagocytosis, and this may limit the inflammatory response to this nonapoptotic form of cell death. The exposure of PS to the outer membrane and to extracellular vesicles is therefore a feature of necroptotic cell death and may serve to provide an immunologically-silent window by generating specific ?find me? and ?eat me? signals. Twit Text FOAVip Phosphatidylserine externalization, necroptotic bodies release, and phagocytosis during necroptosis ????PLoS Biol http://www.kidney.de/pget.php?&tw=1&pmid=28650960 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28650960 #FOAvip English Wikipedia <ref>{{Cite pmid|28650960}}</ref> Phosphatidylserine externalization, ?necroptotic bodies? release, and phagocytosis during necroptosis #MMPMID28650960 Zargarian S; Shlomovitz I; Erlich Z; Hourizadeh A; Ofir-Birin Y; Croker BA; Regev-Rudzki N; Edry-Botzer L; Gerlic M PLoS Biol 2017[Jun]; 15 (6): ä PMID28650960show ga Necroptosis is a regulated, nonapoptotic form of cell death initiated by receptor-interacting protein kinase-3 (RIPK3) and mixed lineage kinase domain-like (MLKL) proteins. It is considered to be a form of regulated necrosis, and, by lacking the ?find me? and ?eat me? signals that are a feature of apoptosis, necroptosis is considered to be inflammatory. One such ?eat me? signal observed during apoptosis is the exposure of phosphatidylserine (PS) on the outer plasma membrane. Here, we demonstrate that necroptotic cells also expose PS after phosphorylated mixed lineage kinase-like (pMLKL) translocation to the membrane. Necroptotic cells that expose PS release extracellular vesicles containing proteins and pMLKL to their surroundings. Furthermore, inhibition of pMLKL after PS exposure can reverse the process of necroptosis and restore cell viability. Finally, externalization of PS by necroptotic cells drives recognition and phagocytosis, and this may limit the inflammatory response to this nonapoptotic form of cell death. The exposure of PS to the outer membrane and to extracellular vesicles is therefore a feature of necroptotic cell death and may serve to provide an immunologically-silent window by generating specific ?find me? and ?eat me? signals. äPhosphatidylserine externalization, ?necroptotic bodies? release, and (epmc).pdf DeepDyve Pubget Overpricing