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10.12688/f1000research.8403.1

http://scihub22266oqcxt.onion/10.12688/f1000research.8403.1
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C4916989!4916989!27347395
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suck abstract from ncbi


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pmid27347395      F1000Res 2016 ; 5 (ä): ä
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  • Recent advances in understanding and treating vasculitis #MMPMID27347395
  • Koster MJ; Warrington KJ
  • F1000Res 2016[]; 5 (ä): ä PMID27347395show ga
  • Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAVs) are near universally fatal conditions if untreated. Although effective therapeutic options are available for these diseases, treatment regimens are associated with both short- and long-term adverse effects. The recent identification of effective B-cell-targeted therapy with an anti-CD20 monoclonal antibody has transformed the treatment landscape of AAV. Questions, nevertheless, remain regarding the appropriate timing, dose, frequency, duration, and long-term effects of treatment. The aim of this article is to provide an overview of the current information, recent advances, ongoing clinical trials, and future treatment possibilities in AAV.
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