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Renal Complications of Immune Checkpoint Blockade #MMPMID28189263
Murakami N; Motwani S; Riella LV
Curr Probl Cancer 2017[Mar]; 41 (2): 100-10 PMID28189263show ga
Immune checkpoint inhibitors have been approved for a variety of cancer species. Renal complications in use of these agents are not very common compared with other immune related adverse events (irAE). However, it is crucial for physicians to recognize and manage renal manifestations of irAE. In this review, we will summarize the up-to-date knowledge of the clinical presentation, pathological features and management of renal irAE. In addition, we will discuss the safety of immune checkpoint inhibitors in patients with chronic kidney disease as well as in kidney transplant recipients.