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Sculpting the Nucleus with Dynamic Microtubules #MMPMID24135226
Guo Y; Zheng Y
Dev Cell 2013[Oct]; 27 (1): 1-2 PMID24135226show ga
How nuclear morphology is regulated during development and disease remains poorly understood. In this issue of Developmental Cell, using a pronuclear assembly assay, Xue et al. (2013) demonstrate that Dppa2, a chromatin-bound microtubule regulator, controls both the morphology and function of the pronucleus by fine-tuning microtubule dynamics.