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10.1007/s12561-014-9111-7

http://scihub22266oqcxt.onion/10.1007/s12561-014-9111-7
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C5006946!5006946!27594925
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suck abstract from ncbi


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pmid27594925      Stat+Biosci 2016 ; 8 (1): 1-7
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  • Strategies for Genomic and Proteomic Profiling of Cancers #MMPMID27594925
  • Omenn GS
  • Stat Biosci 2016[Jun]; 8 (1): 1-7 PMID27594925show ga
  • Omics-based technology platforms have made new kinds of cancer profiling tests feasible. There are several valuable examples in clinical practice, and many more under development. A concerted, transparent process of discovery with lock-down of candidate assays and classifiers and clear specification of intended clinical use is essential. The Institute of Medicine has now proposed a three-stage scheme of confirming and validating analytical findings, validating performance on clinical specimens, and demonstrating explicit clinical utility for an approvable test (Micheel et al., Evolution of translational omics: lessons learned and path forward, 2012).
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