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10.1517/14728214.9.2.223 http://scihub22266oqcxt.onion/10.1517/14728214.9.2.223 15571481!ä!15571481 Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=15571481&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\15571481.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Expert+Opin+Emerg+Drugs 2004 ; 9 (2): 223-36 Nephropedia Template TP {{tp|p=15571481|t=2004. Use of cytokines in infection |pdf=|usr=}}{{15571481}} gab.com Text Use of cytokines in infection JO: Expert Opin Emerg Drugs http://www.kidney.de/pget.php?&tw=1&pmid=15571481 #FOAvip Infectious disease remains an ever-growing health concern worldwide due to increasing antibiotic-resistant microbial strains, immune-compromised populations, international traffic and globalisation, and bioterrorism. There exists an urgent need to develop novel prophylactic and therapeutic strategies. In addition to classic antibiotic therapeutics, immune-modulatory molecules such as cytokines or their inhibitors represent a promising form of antimicrobial therapeutics or immune adjuvant used for the purpose of vaccination. These molecules, in the form of either recombinant protein or transgene, exert their antimicrobial effect by enhancing infectious agent-specific immune activation or memory development, or by dampening undesired inflammatory and immune responses resulting from infection and host defence mechanisms. In the last two decades, a number of cytokine therapy-based experimental and clinical trials have been conducted, and some of these efforts have led to the routine clinical use of cytokines. For instance, although IFNs have been used to treat hepatitis C with great success, many other cytokines are yet to be fully evaluated for their antimicrobial potential. This review discusses the biology and therapeutic potential of selected immune modulatory cytokines and their inhibitors, including granulocyte colony-stimulating factor, granulocyte-macrophage colony-stimulating factor, IFN-gamma, IL-12 and TNF. Twit Text FOAVip Use of cytokines in infection ????Expert Opin Emerg Drugs http://www.kidney.de/pget.php?&tw=1&pmid=15571481 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=15571481 #FOAvip English Wikipedia <ref>{{Cite pmid|15571481}}</ref> Use of cytokines in infection #MMPMID15571481 Aoki N; Xing Z Expert Opin Emerg Drugs 2004[Nov]; 9 (2): 223-36 PMID15571481show ga Infectious disease remains an ever-growing health concern worldwide due to increasing antibiotic-resistant microbial strains, immune-compromised populations, international traffic and globalisation, and bioterrorism. There exists an urgent need to develop novel prophylactic and therapeutic strategies. In addition to classic antibiotic therapeutics, immune-modulatory molecules such as cytokines or their inhibitors represent a promising form of antimicrobial therapeutics or immune adjuvant used for the purpose of vaccination. These molecules, in the form of either recombinant protein or transgene, exert their antimicrobial effect by enhancing infectious agent-specific immune activation or memory development, or by dampening undesired inflammatory and immune responses resulting from infection and host defence mechanisms. In the last two decades, a number of cytokine therapy-based experimental and clinical trials have been conducted, and some of these efforts have led to the routine clinical use of cytokines. For instance, although IFNs have been used to treat hepatitis C with great success, many other cytokines are yet to be fully evaluated for their antimicrobial potential. This review discusses the biology and therapeutic potential of selected immune modulatory cytokines and their inhibitors, including granulocyte colony-stimulating factor, granulocyte-macrophage colony-stimulating factor, IFN-gamma, IL-12 and TNF. |Colony-Stimulating Factors/therapeutic use[MESH] |Communicable Diseases/*drug therapy[MESH] |Cytokines/*therapeutic use[MESH] |Drug Therapy/trends[MESH] |HIV Infections/drug therapy[MESH] |Humans[MESH] |Influenza, Human/drug therapy[MESH] |Interferons/therapeutic use[MESH] |Interleukin-12/therapeutic use[MESH] |Mycoses/drug therapy[MESH]Use of cytokines in infection (epmc).pdf DeepDyve Pubget Overpricing