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10.1681/ASN.2004090754 http://scihub22266oqcxt.onion/10.1681/ASN.2004090754 15647335!ä!15647335 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\15647335.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       J+Am+Soc+Nephrol 2005 ; 16 (2): 299-304 Nephropedia Template TP {{tp|p=15647335|t=2005. Kidney development and disease in the zebrafish |pdf=|usr=}}{{15647335}} gab.com Text Kidney development and disease in the zebrafish JO: J Am Soc Nephrol http://www.kidney.de/pget.php?&tw=1&pmid=15647335 #FOAvip Unraveling the molecular pathogenesis of human disease presents many experimental challenges, not the least of which is that experiments on humans are generally frowned upon. Model organisms, including the zebrafish, allow for experimental analysis of gene function and the detailed characterization of disease processes. Zebrafish have matured as a vertebrate model organism now that genetic tools for targeted "knockdowns" and unbiased mutagenesis approaches are in hand. The fish larval pronephros is a relevant kidney in which to pursue many aspects of human kidney development and disease. This short review outlines recent progress in applying the zebrafish pronephros to issues of human health and development. Twit Text FOAVip Kidney development and disease in the zebrafish ????J Am Soc Nephrol http://www.kidney.de/pget.php?&tw=1&pmid=15647335 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=15647335 #FOAvip English Wikipedia <ref>{{Cite pmid|15647335}}</ref> Kidney development and disease in the zebrafish #MMPMID15647335 Drummond IA J Am Soc Nephrol 2005[Feb]; 16 (2): 299-304 PMID15647335show ga Unraveling the molecular pathogenesis of human disease presents many experimental challenges, not the least of which is that experiments on humans are generally frowned upon. Model organisms, including the zebrafish, allow for experimental analysis of gene function and the detailed characterization of disease processes. Zebrafish have matured as a vertebrate model organism now that genetic tools for targeted "knockdowns" and unbiased mutagenesis approaches are in hand. The fish larval pronephros is a relevant kidney in which to pursue many aspects of human kidney development and disease. This short review outlines recent progress in applying the zebrafish pronephros to issues of human health and development. |Animals[MESH] |Disease Models, Animal[MESH] |Embryonic Structures/*ultrastructure[MESH] |Genomics[MESH] |Humans[MESH] |Kidney/*embryology[MESH] |Models, Animal[MESH] |Nephrons/*embryology/ultrastructure[MESH] |Organogenesis/*physiology[MESH] |Polycystic Kidney Diseases/embryology/*genetics[MESH] |Species Specificity[MESH]Kidney development and disease in the zebrafish (epmc).pdf DeepDyve Pubget Overpricing