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10.1681/ASN.2007070792

http://scihub22266oqcxt.onion/10.1681/ASN.2007070792
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17804670!ä!17804670

suck abstract from ncbi


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pmid17804670      J+Am+Soc+Nephrol 2007 ; 18 (10): 2649-52
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  • Mechanism of hypokalemia in magnesium deficiency #MMPMID17804670
  • Huang CL; Kuo E
  • J Am Soc Nephrol 2007[Oct]; 18 (10): 2649-52 PMID17804670show ga
  • Magnesium deficiency is frequently associated with hypokalemia. Concomitant magnesium deficiency aggravates hypokalemia and renders it refractory to treatment by potassium. Herein is reviewed literature suggesting that magnesium deficiency exacerbates potassium wasting by increasing distal potassium secretion. A decrease in intracellular magnesium, caused by magnesium deficiency, releases the magnesium-mediated inhibition of ROMK channels and increases potassium secretion. Magnesium deficiency alone, however, does not necessarily cause hypokalemia. An increase in distal sodium delivery or elevated aldosterone levels may be required for exacerbating potassium wasting in magnesium deficiency.
  • |Humans[MESH]
  • |Hypokalemia/*complications/metabolism[MESH]
  • |Kidney/metabolism[MESH]
  • |Magnesium Deficiency/*complications/metabolism[MESH]


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