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10.1080/00365510802150158 http://scihub22266oqcxt.onion/10.1080/00365510802150158 18569973!2528839!18569973     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=18569973&cmd=llinks): Failed to open stream: HTTP request failed! 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Neutrophil gelatinase-associated lipocalin (NGAL): a new marker of kidney disease |pdf=|usr=}}{{18569973}} gab.com Text Neutrophil gelatinase-associated lipocalin (NGAL): a new marker of kidney disease JO: Scand J Clin Lab Invest Suppl http://www.kidney.de/pget.php?&tw=1&pmid=18569973 #FOAvip The incidence of both acute kidney injury (AKI, previously referred to as acute renal failure) and chronic kidney disease (CKD) is reaching epidemic proportions. In both situations, early intervention can significantly improve the prognosis. However, the paucity of early, predictive, non-invasive biomarkers has impaired our ability to institute potentially effective therapies for these common clinical conditions in a timely manner. The current status of one of the most promising novel biomarkers, namely neutrophil gelatinase-associated lipocalin (NGAL), is presented in this review. The evidence for the role of NGAL measurements in a variety of clinical situations leading to AKI (cardiac surgery, kidney transplantation, contrast nephropathy, haemolytic uraemic syndrome and in the intensive care setting) or to CKD (lupus nephritis, glomerulonephritides, obstruction, dysplasia, polycystic kidney disease, IgA nephropathy) is explored. The emerging utility of standardized clinical platforms for reliable measurement of NGAL in plasma (Triage NGAL Device; Biosite Incorporated) and urine (ARCHITECT analyzer; Abbott Diagnostics) is also discussed. It will be important in future studies to validate the sensitivity and specificity of NGAL concentration measurements in clinical samples from large cohorts and from multiple clinical situations. Such studies will be facilitated by the anticipated widespread availability of standardized commercial tools in the near future. Twit Text FOAVip Neutrophil gelatinase-associated lipocalin (NGAL): a new marker of kidney disease ????Scand J Clin Lab Invest Suppl http://www.kidney.de/pget.php?&tw=1&pmid=18569973 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=18569973 #FOAvip English Wikipedia <ref>{{Cite pmid|18569973}}</ref> Neutrophil gelatinase-associated lipocalin (NGAL): a new marker of kidney disease #MMPMID18569973 Devarajan P Scand J Clin Lab Invest Suppl 2008[]; 241 (ä): 89-94 PMID18569973show ga The incidence of both acute kidney injury (AKI, previously referred to as acute renal failure) and chronic kidney disease (CKD) is reaching epidemic proportions. In both situations, early intervention can significantly improve the prognosis. However, the paucity of early, predictive, non-invasive biomarkers has impaired our ability to institute potentially effective therapies for these common clinical conditions in a timely manner. The current status of one of the most promising novel biomarkers, namely neutrophil gelatinase-associated lipocalin (NGAL), is presented in this review. The evidence for the role of NGAL measurements in a variety of clinical situations leading to AKI (cardiac surgery, kidney transplantation, contrast nephropathy, haemolytic uraemic syndrome and in the intensive care setting) or to CKD (lupus nephritis, glomerulonephritides, obstruction, dysplasia, polycystic kidney disease, IgA nephropathy) is explored. The emerging utility of standardized clinical platforms for reliable measurement of NGAL in plasma (Triage NGAL Device; Biosite Incorporated) and urine (ARCHITECT analyzer; Abbott Diagnostics) is also discussed. It will be important in future studies to validate the sensitivity and specificity of NGAL concentration measurements in clinical samples from large cohorts and from multiple clinical situations. Such studies will be facilitated by the anticipated widespread availability of standardized commercial tools in the near future. |Acute Disease[MESH] |Acute-Phase Proteins/*analysis/urine[MESH] |Biomarkers/*analysis[MESH] |Chronic Disease[MESH] |Humans[MESH] |Kidney Diseases/blood/*diagnosis/urine[MESH] |Lipocalin-2[MESH] |Lipocalins/*analysis/blood/urine[MESH]Neutrophil gelatinase-associated lipocalin (NGAL): a new marker of kid(epmc).pdf DeepDyve Pubget Overpricing