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suck abstract from ncbi


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pmid18816241      Exp+Clin+Transplant 2008 ; 6 (2): 137-43
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  • Parvovirus B19 microepidemic in renal transplant recipients with thrombotic microangiopathy and allograft vasculitis #MMPMID18816241
  • Ardalan MR; Shoja MM; Tubbs RS; Jayne D
  • Exp Clin Transplant 2008[Jun]; 6 (2): 137-43 PMID18816241show ga
  • Parvovirus B-19 (B-19) can lead to various clinical scenarios in renal transplant recipients. Here, we report a B-19 microepidemic that occurred between January and March 2007, involving renal transplant recipients from a single center in Tabriz, Iran. We observed 6 patients in whom there was a temporal association between active B-19 infection and thrombotic microangiopathy and intrarenal small and medium-sized vessel vasculitis. Patients typically presented with deteriorating renal allograft function and anemia, and laboratory findings revealed thrombotic microangiopathy. Ultimately, extensive endothelial injury and renal allograft vasculitis that mimicked a vascular rejection ensued. In conclusion, B-19-related thrombotic microangiopathy may precede allograft vasculitis in renal transplant recipients. A high index of suspicion is required for early diagnosis and treatment of B-19 infection. To the best of our knowledge, this series represents the first report of B-19-related renal allograft vasculitis in the English literature.
  • |*Kidney Transplantation[MESH]
  • |*Parvovirus B19, Human[MESH]
  • |*Postoperative Complications[MESH]
  • |Adult[MESH]
  • |Disease Outbreaks[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Iran[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Parvoviridae Infections/*complications/diagnosis/*epidemiology[MESH]
  • |Thrombosis/diagnosis/*virology[MESH]


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