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Disturbance of cerebral neuronal migration following congenital parvovirus B19 infection #MMPMID19060481
Pistorius LR; Smal J; de Haan TR; Page-Christiaens GC; Verboon-Maciolek M; Oepkes D; de Vries LS
Fetal Diagn Ther 2008[]; 24 (4): 491-4 PMID19060481show ga
OBJECTIVE: We describe the clinical course of an infant who presented with severe fetal anemia and fetal hydrops following congenital parvovirus B19 infection before 16 gestational weeks. The fetus was treated by cordocentesis and intrauterine transfusion at 18 weeks. RESULTS: The infant demonstrated mild unilateral ventriculomegaly on antenatal magnetic resonance imaging, and polymicrogyria and heterotopia on postnatal magnetic resonance imaging. CONCLUSION: This adds to the evidence in recent literature of central nervous system damage associated with congenital parvovirus B19 infection.