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10.1016/j.virol.2009.04.016 http://scihub22266oqcxt.onion/10.1016/j.virol.2009.04.016 19450862!ä!19450862 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\19450862.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Virology 2009 ; 390 (1): 56-63 Nephropedia Template TP {{tp|p=19450862|t=2009. Antibody-mediated opsonization of red blood cells in parvovirus B19 infection |pdf=|usr=}}{{19450862}} gab.com Text Antibody-mediated opsonization of red blood cells in parvovirus B19 infection JO: Virology http://www.kidney.de/pget.php?&tw=1&pmid=19450862 #FOAvip Red blood cells (RBCs) express abundantly parvovirus B19 receptor, and their role in the dissemination or clearance of B19 infection is unknown. In this study, we report that in early, acute or persistent infection, B19 viremia is mostly associated with RBCs. The capacity of different patients' plasma or IgG to opsonize RBCs collected from patients with early B19 infection, was investigated. The highest opsonization activity was observed with plasma or IgG fractions from patients with past B19 infection. In contrast, IgG samples from patients with acute or persistent infection showed no or little opsonization activity. The depletion of antibodies specific to B19 VP1, but not VP2, from IgG samples, resulted in a significant suppression of opsonization. Furthermore, IgG samples preincubated with heated B19 particles exposing VP1-unique (VP1u) region were unable to opsonize RBCs. These observations clearly suggest a role for anti-VP1u IgG in the opsonization of RBC-bound B19 particles. Twit Text FOAVip Antibody-mediated opsonization of red blood cells in parvovirus B19 infection ????Virology http://www.kidney.de/pget.php?&tw=1&pmid=19450862 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=19450862 #FOAvip English Wikipedia <ref>{{Cite pmid|19450862}}</ref> Antibody-mediated opsonization of red blood cells in parvovirus B19 infection #MMPMID19450862 Chehadeh W; Halim MA; Al-Nakib W Virology 2009[Jul]; 390 (1): 56-63 PMID19450862show ga Red blood cells (RBCs) express abundantly parvovirus B19 receptor, and their role in the dissemination or clearance of B19 infection is unknown. In this study, we report that in early, acute or persistent infection, B19 viremia is mostly associated with RBCs. The capacity of different patients' plasma or IgG to opsonize RBCs collected from patients with early B19 infection, was investigated. The highest opsonization activity was observed with plasma or IgG fractions from patients with past B19 infection. In contrast, IgG samples from patients with acute or persistent infection showed no or little opsonization activity. The depletion of antibodies specific to B19 VP1, but not VP2, from IgG samples, resulted in a significant suppression of opsonization. Furthermore, IgG samples preincubated with heated B19 particles exposing VP1-unique (VP1u) region were unable to opsonize RBCs. These observations clearly suggest a role for anti-VP1u IgG in the opsonization of RBC-bound B19 particles. |Adolescent[MESH] |Adult[MESH] |Aged[MESH] |Antibodies, Viral/*blood[MESH] |Capsid Proteins/immunology[MESH] |Case-Control Studies[MESH] |Child[MESH] |Child, Preschool[MESH] |Erythema Infectiosum/*blood/*immunology/virology[MESH] |Erythrocytes/*immunology/*virology[MESH] |Female[MESH] |Humans[MESH] |Immunoglobulin G/blood[MESH] |Immunoglobulin M/blood[MESH] |In Vitro Techniques[MESH] |Male[MESH] |Middle Aged[MESH] |Opsonin Proteins/*blood[MESH] |Parvoviridae Infections/*blood/*immunology/virology[MESH] |Parvovirus B19, Human/*immunology/*pathogenicity/physiology[MESH]Antibody-mediated opsonization of red blood cells in parvovirus B19 in(epmc).pdf DeepDyve Pubget Overpricing