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10.4161/rna.7.3.11692 http://scihub22266oqcxt.onion/10.4161/rna.7.3.11692 20458188!3748720!20458188     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\20458188.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       RNA+Biol 2010 ; 7 (3): 296-9 Nephropedia Template TP {{tp|p=20458188|t=2010. MicroRNAs in kidney development: lessons from the frog |pdf=|usr=}}{{20458188}} gab.com Text MicroRNAs in kidney development: lessons from the frog JO: RNA Biol http://www.kidney.de/pget.php?&tw=1&pmid=20458188 #FOAvip Kidney development is a paradigm of how multiple cell types are integrated into highly specialized epithelial structures via various inductive events. A network of transcription factors and signaling pathways have been identified as crucial regulators. The recent discovery of a group of small, non-coding RNAs, microRNAs (miRNAs), has added a new layer of complexity. Studies using the pronephric kidney of Xenopus and the metanephric kidney of mouse have demonstrated that a tight regulation of mRNA stability and translation efficiency by miRNAs is very important as well. The interplay between miRNAs and the transcriptional network provides plasticity and robustness to the system. Importantly, miRNAs are not only necessary for early aspects of kidney development, but also later in life. As such they may provide a mean to maintain/modulate kidney function during homeostasis and injury. Twit Text FOAVip MicroRNAs in kidney development: lessons from the frog ????RNA Biol http://www.kidney.de/pget.php?&tw=1&pmid=20458188 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=20458188 #FOAvip English Wikipedia <ref>{{Cite pmid|20458188}}</ref> MicroRNAs in kidney development: lessons from the frog #MMPMID20458188 Wessely O; Agrawal R; Tran U RNA Biol 2010[May]; 7 (3): 296-9 PMID20458188show ga Kidney development is a paradigm of how multiple cell types are integrated into highly specialized epithelial structures via various inductive events. A network of transcription factors and signaling pathways have been identified as crucial regulators. The recent discovery of a group of small, non-coding RNAs, microRNAs (miRNAs), has added a new layer of complexity. Studies using the pronephric kidney of Xenopus and the metanephric kidney of mouse have demonstrated that a tight regulation of mRNA stability and translation efficiency by miRNAs is very important as well. The interplay between miRNAs and the transcriptional network provides plasticity and robustness to the system. Importantly, miRNAs are not only necessary for early aspects of kidney development, but also later in life. As such they may provide a mean to maintain/modulate kidney function during homeostasis and injury. |*Models, Animal[MESH] |Animals[MESH] |Anura/*embryology/*genetics/physiology[MESH] |Embryo, Nonmammalian[MESH] |Humans[MESH] |Kidney/*embryology/growth & development/metabolism[MESH] |Mice[MESH] |MicroRNAs/genetics/metabolism/*physiology[MESH] |Models, Biological[MESH]MicroRNAs in kidney development: lessons from the frog (epmc).pdf DeepDyve Pubget Overpricing