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10.1111/j.1600-6143.2011.03679.x http://scihub22266oqcxt.onion/10.1111/j.1600-6143.2011.03679.x 21812927!ä!21812927 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\21812927.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Am+J+Transplant 2011 ; 11 (10): 2221-7 Nephropedia Template TP {{tp|p=21812927|t=2011. Urinary miR-210 as a mediator of acute T-cell mediated rejection in renal allograft recipients |pdf=|usr=}}{{21812927}} gab.com Text Urinary miR-210 as a mediator of acute T-cell mediated rejection in renal allograft recipients JO: Am J Transplant http://www.kidney.de/pget.php?&tw=1&pmid=21812927 #FOAvip MicroRNAs (miRNAs) are small ribonucleotides regulating gene expression. Circulating miRNAs are remarkably stable in the blood. We tested whether miRNAs are also detectable in urine and may serve as new predictors of outcome in renal transplant patients with acute rejection. We profiled urinary miRNAs of stable transplant patients and transplant patients with acute rejection. The miR-10a, miR-10b and miR-210 were strongly deregulated in urine of the patients with acute rejection. We confirmed these data in urine of a validation cohort of 62 patients with acute rejection, 19 control transplant patients without rejection and 13 stable transplant patients with urinary tract infection by quantitative RT-PCR. The miR-10b and miR-210 were downregulated and miR-10a upregulated in patients with acute rejection compared to controls. Only miR-210 differed between patients with acute rejection when compared to stable transplant patients with urinary tract infection or transplant patients before/after rejection. Low miR-210 levels were associated with higher decline in GFR 1 year after transplantation. Selected miRNAs are strongly altered in urine of the patients with acute renal allograft rejection. The miR-210 levels identify patients with acute rejection and predict long-term kidney function. Urinary miR-210 may thus serve as a novel biomarker of acute kidney rejection. Twit Text FOAVip Urinary miR-210 as a mediator of acute T-cell mediated rejection in renal allograft recipients ????Am J Transplant http://www.kidney.de/pget.php?&tw=1&pmid=21812927 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=21812927 #FOAvip English Wikipedia <ref>{{Cite pmid|21812927}}</ref> Urinary miR-210 as a mediator of acute T-cell mediated rejection in renal allograft recipients #MMPMID21812927 Lorenzen JM; Volkmann I; Fiedler J; Schmidt M; Scheffner I; Haller H; Gwinner W; Thum T Am J Transplant 2011[Oct]; 11 (10): 2221-7 PMID21812927show ga MicroRNAs (miRNAs) are small ribonucleotides regulating gene expression. Circulating miRNAs are remarkably stable in the blood. We tested whether miRNAs are also detectable in urine and may serve as new predictors of outcome in renal transplant patients with acute rejection. We profiled urinary miRNAs of stable transplant patients and transplant patients with acute rejection. The miR-10a, miR-10b and miR-210 were strongly deregulated in urine of the patients with acute rejection. We confirmed these data in urine of a validation cohort of 62 patients with acute rejection, 19 control transplant patients without rejection and 13 stable transplant patients with urinary tract infection by quantitative RT-PCR. The miR-10b and miR-210 were downregulated and miR-10a upregulated in patients with acute rejection compared to controls. Only miR-210 differed between patients with acute rejection when compared to stable transplant patients with urinary tract infection or transplant patients before/after rejection. Low miR-210 levels were associated with higher decline in GFR 1 year after transplantation. Selected miRNAs are strongly altered in urine of the patients with acute renal allograft rejection. The miR-210 levels identify patients with acute rejection and predict long-term kidney function. Urinary miR-210 may thus serve as a novel biomarker of acute kidney rejection. |Adolescent[MESH] |Adult[MESH] |Aged[MESH] |Female[MESH] |Graft Rejection/*immunology[MESH] |Humans[MESH] |Kidney Transplantation/*immunology[MESH] |Male[MESH] |MicroRNAs/*urine[MESH] |Middle Aged[MESH] |T-Lymphocytes/*immunology[MESH] |Transcriptome[MESH] |Transplantation, Homologous[MESH]Urinary miR-210 as a mediator of acute T-cell mediated rejection in re(epmc).pdf DeepDyve Pubget Overpricing