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10.1371/journal.pone.0064391

http://scihub22266oqcxt.onion/10.1371/journal.pone.0064391
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suck abstract from ncbi


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pmid23737981      PLoS+One 2013 ; 8 (5): e64391
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  • Prevalence of human parvovirus B19, bocavirus, and PARV4 in blood samples from the general population of China and lack of a correlation between parvovirus and hepatitis B co-infection #MMPMID23737981
  • Tong R; Shen L; Yin W; Zhou W; Lu J; Zheng M; Bi S; Lou Y; Tan W
  • PLoS One 2013[]; 8 (5): e64391 PMID23737981show ga
  • Few comprehensive studies have investigated viraemia caused by human parvoviruses (HPAVs) in China. A total of 1626 of blood samples were collected from non-HBV and HBV infected Chinese subjects (adults, N = 1279; children, N = 347) from south-western and south-eastern China. DNA from three HPAVs was detected in blood samples using PCR-based assays. The epidemiological profiles and association with HBV co-infection were also analysed. Of the 1626 blood samples tested, 138 (8.49%) were found to exhibit HPAV viraemia, including 3.51% with B19, 3.75% with HBoV and 2.52% with PARV4. The presence of B19 DNA in both child and adult, as well as that of PARV4 DNA in adult,from the south-western region was significantly higher than that from the south-eastern region (P = 0.006 for B19 in children; P = 0.026 for B19 in adults; and P = 0.014 for PARV4 in adult).However, the frequency of HBoV DNA in adults from the south-western region was significantly lower than that observed in adults from the south-eastern region (P = 0.001). Furthermore, HBoV was more prevalence in male (4.9%) than in female (1.4%) individuals. In addition, no significant correlation between HBV and HPAV co-infection was found using serum samples from Chinese adults. In conclusions,the molecular prevalence of three HPAVs in blood samples exhibited variation among different populations depending on area, age and gender; No association between HPAV and HBV infection in adults was found. Our data provide a basis for improving blood safety and preventing HPAV infection in China.
  • |Adolescent[MESH]
  • |Adult[MESH]
  • |Age Distribution[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |Asymptomatic Diseases[MESH]
  • |Child[MESH]
  • |Child, Preschool[MESH]
  • |China/epidemiology[MESH]
  • |Coinfection/*blood/epidemiology/*virology[MESH]
  • |Female[MESH]
  • |Hepatitis B/*blood/epidemiology/*virology[MESH]
  • |Human bocavirus/*isolation & purification/physiology[MESH]
  • |Humans[MESH]
  • |Infant[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Parvoviridae Infections/*blood/epidemiology[MESH]
  • |Parvovirus B19, Human/*isolation & purification/physiology[MESH]
  • |Polymerase Chain Reaction[MESH]
  • |Prevalence[MESH]
  • |Sex Distribution[MESH]


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