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10.1186/cc13787

http://scihub22266oqcxt.onion/10.1186/cc13787
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24886820!4035855!24886820
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suck abstract from ncbi


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pmid24886820      Crit+Care 2014 ; 18 (2): 216
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  • Is boosting the immune system in sepsis appropriate? #MMPMID24886820
  • Cavaillon JM; Eisen D; Annane D
  • Crit Care 2014[Mar]; 18 (2): 216 PMID24886820show ga
  • A relative immunosuppression is observed in patients after sepsis, trauma, burns, or any severe insults. It is currently proposed that selected patients will benefit from treatment aimed at boosting their immune systems. However, the host immune response needs to be considered in context with pathogen-type, timing,and mainly tissue specificity. Indeed, the immune status of leukocytes is not universally decreased and their activated status in tissues contributes to organ failure. Accordingly, any new immune-stimulatory therapeutic intervention should take into consideration potentially deleterious effects in some situations.
  • |Animals[MESH]
  • |Humans[MESH]
  • |Immune System/drug effects/*immunology[MESH]
  • |Immunity, Innate/drug effects/immunology[MESH]
  • |Immunologic Factors/pharmacology/*therapeutic use[MESH]


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