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10.1016/j.trsl.2015.06.006 http://scihub22266oqcxt.onion/10.1016/j.trsl.2015.06.006 26118952!4487391!26118952     free     free     free Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26118952.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Transl+Res 2016 ; 167 (1): 125-37 Nephropedia Template TP {{tp|p=26118952|t=2016. Targeting the inflammasome in rheumatic diseases |pdf=|usr=}}{{26118952}} gab.com Text Targeting the inflammasome in rheumatic diseases JO: Transl Res http://www.kidney.de/pget.php?&tw=1&pmid=26118952 #FOAvip Activation of the inflammasome, a protein complex responsible for many cellular functions, including the activation of the proinflammatory cytokines interleukin (IL)-1beta and IL-18, has been identified as a key participant in many rheumatic diseases including autoimmune, inflammatory, and autoinflammatory syndromes. This review will discuss the recent advances in understanding the role of this complex in various rheumatic diseases. Furthermore, it will focus on available therapies, which directly and indirectly target the inflammasome and its downstream cytokines to quiet inflammation and possibly dampen autoimmune processes. Twit Text FOAVip Targeting the inflammasome in rheumatic diseases ????Transl Res http://www.kidney.de/pget.php?&tw=1&pmid=26118952 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26118952 #FOAvip English Wikipedia <ref>{{Cite pmid|26118952}}</ref> Targeting the inflammasome in rheumatic diseases #MMPMID26118952 McCoy SS; Stannard J; Kahlenberg JM Transl Res 2016[Jan]; 167 (1): 125-37 PMID26118952show ga Activation of the inflammasome, a protein complex responsible for many cellular functions, including the activation of the proinflammatory cytokines interleukin (IL)-1beta and IL-18, has been identified as a key participant in many rheumatic diseases including autoimmune, inflammatory, and autoinflammatory syndromes. This review will discuss the recent advances in understanding the role of this complex in various rheumatic diseases. Furthermore, it will focus on available therapies, which directly and indirectly target the inflammasome and its downstream cytokines to quiet inflammation and possibly dampen autoimmune processes. |*Drug Delivery Systems[MESH] |Animals[MESH] |Cytokines/metabolism[MESH] |Humans[MESH] |Inflammasomes/*drug effects[MESH] |Inflammation/metabolism[MESH] |Rheumatic Diseases/*drug therapy/immunology[MESH]Targeting the inflammasome in rheumatic diseases (epmc).pdf DeepDyve Pubget Overpricing