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10.1155/2016/6269157 http://scihub22266oqcxt.onion/10.1155/2016/6269157 27034965!4789470!27034965     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27034965&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27034965.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       J+Immunol+Res 2016 ; 2016 (ä): 6269157 Nephropedia Template TP {{tp|p=27034965|t=2016. Breakdown of Immune Tolerance in Systemic Lupus Erythematosus by Dendritic Cells |pdf=|usr=}}{{27034965}} gab.com Text Breakdown of Immune Tolerance in Systemic Lupus Erythematosus by Dendritic Cells JO: J Immunol Res http://www.kidney.de/pget.php?&tw=1&pmid=27034965 #FOAvip Dendritic cells (DC) play an important role in the pathogenesis of systemic lupus erythematosus (SLE), an autoimmune disease with multiple tissue manifestations. In this review, we summarize recent studies on the roles of conventional DC and plasmacytoid DC in the development of both murine lupus and human SLE. In the past decade, studies using selective DC depletions have demonstrated critical roles of DC in lupus progression. Comprehensive in vitro and in vivo studies suggest activation of DC by self-antigens in lupus pathogenesis, followed by breakdown of immune tolerance to self. Potential treatment strategies targeting DC have been developed. However, many questions remain regarding the mechanisms by which DC modulate lupus pathogenesis that require further investigations. Twit Text FOAVip Breakdown of Immune Tolerance in Systemic Lupus Erythematosus by Dendritic Cells ????J Immunol Res http://www.kidney.de/pget.php?&tw=1&pmid=27034965 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27034965 #FOAvip English Wikipedia <ref>{{Cite pmid|27034965}}</ref> Breakdown of Immune Tolerance in Systemic Lupus Erythematosus by Dendritic Cells #MMPMID27034965 Liao X; Reihl AM; Luo XM J Immunol Res 2016[]; 2016 (ä): 6269157 PMID27034965show ga Dendritic cells (DC) play an important role in the pathogenesis of systemic lupus erythematosus (SLE), an autoimmune disease with multiple tissue manifestations. In this review, we summarize recent studies on the roles of conventional DC and plasmacytoid DC in the development of both murine lupus and human SLE. In the past decade, studies using selective DC depletions have demonstrated critical roles of DC in lupus progression. Comprehensive in vitro and in vivo studies suggest activation of DC by self-antigens in lupus pathogenesis, followed by breakdown of immune tolerance to self. Potential treatment strategies targeting DC have been developed. However, many questions remain regarding the mechanisms by which DC modulate lupus pathogenesis that require further investigations. |*Immune Tolerance[MESH] |Animals[MESH] |Autoantigens/genetics/immunology[MESH] |Autoimmunity[MESH] |Cell Lineage/*immunology[MESH] |Dendritic Cells/*immunology/pathology[MESH] |Disease Models, Animal[MESH] |Disease Progression[MESH] |Gene Expression Regulation/*immunology[MESH] |Humans[MESH] |Interferon-gamma/genetics/immunology[MESH] |Lupus Erythematosus, Systemic/genetics/*immunology/pathology[MESH] |Mice[MESH] |Signal Transduction[MESH]Breakdown of Immune Tolerance in Systemic Lupus Erythematosus by Dendr(epmc).pdf DeepDyve Pubget Overpricing