Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1016/j.pharmthera.2016.03.015 http://scihub22266oqcxt.onion/10.1016/j.pharmthera.2016.03.015 27108948!5123830!27108948     free     free     free Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27108948.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Pharmacol+Ther 2016 ; 163 (ä): 58-73 Nephropedia Template TP {{tp|p=27108948|t=2016. Renoprotective approaches and strategies in acute kidney injury |pdf=|usr=}}{{27108948}} gab.com Text Renoprotective approaches and strategies in acute kidney injury JO: Pharmacol Ther http://www.kidney.de/pget.php?&tw=1&pmid=27108948 #FOAvip Acute kidney injury (AKI) is a major renal disease associated with high mortality rate and increasing prevalence. Decades of research have suggested numerous chemical and biological agents with beneficial effects in AKI. In addition, cell therapy and molecular targeting have been explored for reducing kidney tissue damage and promoting kidney repair or recovery from AKI. Mechanistically, these approaches may mitigate oxidative stress, inflammation, cell death, and mitochondrial and other organellar damage, or activate cytoprotective mechanisms such as autophagy and pro-survival factors. However, none of these findings has been successfully translated into clinical treatment of AKI. In this review, we analyze these findings and propose experimental strategies for the identification of renoprotective agents or methods with clinical potential. Moreover, we propose the consideration of combination therapy by targeting multiple targets in AKI. Twit Text FOAVip Renoprotective approaches and strategies in acute kidney injury ????Pharmacol Ther http://www.kidney.de/pget.php?&tw=1&pmid=27108948 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27108948 #FOAvip English Wikipedia <ref>{{Cite pmid|27108948}}</ref> Renoprotective approaches and strategies in acute kidney injury #MMPMID27108948 Yang Y; Song M; Liu Y; Liu H; Sun L; Peng Y; Liu F; Venkatachalam MA; Dong Z Pharmacol Ther 2016[Jul]; 163 (ä): 58-73 PMID27108948show ga Acute kidney injury (AKI) is a major renal disease associated with high mortality rate and increasing prevalence. Decades of research have suggested numerous chemical and biological agents with beneficial effects in AKI. In addition, cell therapy and molecular targeting have been explored for reducing kidney tissue damage and promoting kidney repair or recovery from AKI. Mechanistically, these approaches may mitigate oxidative stress, inflammation, cell death, and mitochondrial and other organellar damage, or activate cytoprotective mechanisms such as autophagy and pro-survival factors. However, none of these findings has been successfully translated into clinical treatment of AKI. In this review, we analyze these findings and propose experimental strategies for the identification of renoprotective agents or methods with clinical potential. Moreover, we propose the consideration of combination therapy by targeting multiple targets in AKI. |Acute Kidney Injury/*drug therapy/*prevention & control[MESH] |Animals[MESH] |Autophagy[MESH] |Cell- and Tissue-Based Therapy/methods[MESH] |Complementary Therapies/methods[MESH] |Disease Models, Animal[MESH] |Gene Expression/drug effects/physiology[MESH] |Humans[MESH] |Inflammation Mediators/metabolism[MESH] |Inflammation/physiopathology[MESH] |Kidney Tubules/drug effects[MESH]Renoprotective approaches and strategies in acute kidney injury (epmc).pdf DeepDyve Pubget Overpricing