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10.1161/STROKEAHA.117.018272 http://scihub22266oqcxt.onion/10.1161/STROKEAHA.117.018272 28864597!5614850!28864597     free     free     free Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28864597.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Stroke 2017 ; 48 (10): 2875-2877 Nephropedia Template TP {{tp|p=28864597|t=2017. Parvovirus B19 Infection in Children With Arterial Ischemic Stroke |pdf=|usr=}}{{28864597}} gab.com Text Parvovirus B19 Infection in Children With Arterial Ischemic Stroke JO: Stroke http://www.kidney.de/pget.php?&tw=1&pmid=28864597 #FOAvip BACKGROUND AND PURPOSE: Case-control studies suggest that acute infection transiently increases the risk of childhood arterial ischemic stroke. We hypothesized that an unbiased pathogen discovery approach utilizing MassTag-polymerase chain reaction would identify pathogens in the blood of childhood arterial ischemic stroke cases. METHODS: The multicenter international VIPS study (Vascular Effects of Infection in Pediatric Stroke) enrolled arterial ischemic stroke cases, and stroke-free controls, aged 29 days through 18 years. Parental interview included questions on recent infections. In this pilot study, we used MassTag-polymerase chain reaction to test the plasma of the first 161 cases and 34 controls enrolled for a panel of 28 common bacterial and viral pathogens. RESULTS: Pathogen DNA was detected in no controls and 14 cases (8.7%): parvovirus B19 (n=10), herpesvirus 6 (n=2), adenovirus (n=1), and rhinovirus 6C (n=1). Parvovirus B19 infection was confirmed by serologies in all 10; infection was subclinical in 8. Four cases with parvovirus B19 had underlying congenital heart disease, whereas another 5 had a distinct arteriopathy involving a long-segment stenosis of the distal internal carotid and proximal middle cerebral arteries. CONCLUSIONS: Using MassTag-polymerase chain reaction, we detected parvovirus B19-a virus known to infect erythrocytes and endothelial cells-in some cases of childhood arterial ischemic stroke. This approach can generate new, testable hypotheses about childhood stroke pathogenesis. Twit Text FOAVip Parvovirus B19 Infection in Children With Arterial Ischemic Stroke ????Stroke http://www.kidney.de/pget.php?&tw=1&pmid=28864597 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28864597 #FOAvip English Wikipedia <ref>{{Cite pmid|28864597}}</ref> Parvovirus B19 Infection in Children With Arterial Ischemic Stroke #MMPMID28864597 Fullerton HJ; Luna JM; Wintermark M; Hills NK; Tokarz R; Li Y; Glaser C; DeVeber GA; Lipkin WI; Elkind MSV Stroke 2017[Oct]; 48 (10): 2875-2877 PMID28864597show ga BACKGROUND AND PURPOSE: Case-control studies suggest that acute infection transiently increases the risk of childhood arterial ischemic stroke. We hypothesized that an unbiased pathogen discovery approach utilizing MassTag-polymerase chain reaction would identify pathogens in the blood of childhood arterial ischemic stroke cases. METHODS: The multicenter international VIPS study (Vascular Effects of Infection in Pediatric Stroke) enrolled arterial ischemic stroke cases, and stroke-free controls, aged 29 days through 18 years. Parental interview included questions on recent infections. In this pilot study, we used MassTag-polymerase chain reaction to test the plasma of the first 161 cases and 34 controls enrolled for a panel of 28 common bacterial and viral pathogens. RESULTS: Pathogen DNA was detected in no controls and 14 cases (8.7%): parvovirus B19 (n=10), herpesvirus 6 (n=2), adenovirus (n=1), and rhinovirus 6C (n=1). Parvovirus B19 infection was confirmed by serologies in all 10; infection was subclinical in 8. Four cases with parvovirus B19 had underlying congenital heart disease, whereas another 5 had a distinct arteriopathy involving a long-segment stenosis of the distal internal carotid and proximal middle cerebral arteries. CONCLUSIONS: Using MassTag-polymerase chain reaction, we detected parvovirus B19-a virus known to infect erythrocytes and endothelial cells-in some cases of childhood arterial ischemic stroke. This approach can generate new, testable hypotheses about childhood stroke pathogenesis. |*Parvovirus B19, Human/isolation & purification[MESH] |Adolescent[MESH] |Brain Ischemia/diagnosis/*epidemiology/virology[MESH] |Case-Control Studies[MESH] |Child[MESH] |Child, Preschool[MESH] |Female[MESH] |Humans[MESH] |Infant[MESH] |Male[MESH] |Parvoviridae Infections/diagnosis/*epidemiology[MESH] |Pilot Projects[MESH]Parvovirus B19 Infection in Children With Arterial Ischemic Stroke (epmc).pdf DeepDyve Pubget Overpricing