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10.1210/jcem-67-6-1134 http://scihub22266oqcxt.onion/10.1210/jcem-67-6-1134 2973471!�!2973471 Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=2973471&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\2973471.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       J+Clin+Endocrinol+Metab 1988 ; 67 (6): 1134-9 Nephropedia Template TP {{tp|p=2973471|t=1988. Atrial natriuretic hormone has biological effects in man at physiological plasma concentrations |pdf=|usr=}}{{2973471}} gab.com Text Atrial natriuretic hormone has biological effects in man at physiological plasma concentrations JO: J Clin Endocrinol Metab http://www.kidney.de/pget.php?&tw=1&pmid=2973471 #FOAvip Whether atrial natriuretic hormone (ANH) has biological effects at physiological plasma levels in man is not known. Accordingly, we investigated the effects of a 3-h low dose infusion of human ANF (0.75 pmol/kg.min; i.e. 0.0023 micrograms/kg.min) in six normal men, whose sodium intake was normal while sitting, in a single blind, random order, placebo-controlled study. The ANF infusions induced changes in plasma ANH concentrations entirely within the range for normal subjects. The small increases in plasma ANH values were associated with a significant rise in urinary excretion of sodium, magnesium, calcium, and cGMP. PRA and plasma aldosterone concentrations uniformly decreased to 50% and 64% of placebo values, respectively. Systolic and mean arterial pressures fell significantly from preinfusion values during the ANH infusions. These findings constitute strong evidence that ANH is a hormone of physiological significance in the regulation of body fluid volumes in normal man. Twit Text FOAVip Atrial natriuretic hormone has biological effects in man at physiological plasma concentrations ????J Clin Endocrinol Metab http://www.kidney.de/pget.php?&tw=1&pmid=2973471 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=2973471 #FOAvip English Wikipedia <ref>{{Cite pmid|2973471}}</ref> Atrial natriuretic hormone has biological effects in man at physiological plasma concentrations #MMPMID2973471 Richards AM; McDonald D; Fitzpatrick MA; Nicholls MG; Espiner EA; Ikram H; Jans S; Grant S; Yandle T J Clin Endocrinol Metab 1988[Dec]; 67 (6): 1134-9 PMID2973471show ga Whether atrial natriuretic hormone (ANH) has biological effects at physiological plasma levels in man is not known. Accordingly, we investigated the effects of a 3-h low dose infusion of human ANF (0.75 pmol/kg.min; i.e. 0.0023 micrograms/kg.min) in six normal men, whose sodium intake was normal while sitting, in a single blind, random order, placebo-controlled study. The ANF infusions induced changes in plasma ANH concentrations entirely within the range for normal subjects. The small increases in plasma ANH values were associated with a significant rise in urinary excretion of sodium, magnesium, calcium, and cGMP. PRA and plasma aldosterone concentrations uniformly decreased to 50% and 64% of placebo values, respectively. Systolic and mean arterial pressures fell significantly from preinfusion values during the ANH infusions. These findings constitute strong evidence that ANH is a hormone of physiological significance in the regulation of body fluid volumes in normal man. |Adult[MESH] |Atrial Natriuretic Factor/administration & dosage/blood/*pharmacology[MESH] |Hemodynamics/drug effects[MESH] |Humans[MESH] |Infusions, Intravenous[MESH] |Male[MESH] |Middle Aged[MESH] |Natriuresis/drug effects[MESH] |Placebos[MESH] |Random Allocation[MESH] |Renin-Angiotensin System/drug effects[MESH]Atrial natriuretic hormone has biological effects in man at physiologi(epmc).pdf DeepDyve Pubget Overpricing