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10.1002/jmv.25682 http://scihub22266oqcxt.onion/10.1002/jmv.25682 31967321!7138088!31967321     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=31967321&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\31967321.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       J+Med+Virol 2020 ; 92 (4): 433-440 Nephropedia Template TP {{tp|p=31967321|t=2020. Cross-species transmission of the newly identified coronavirus 2019-nCoV |pdf=|usr=}}{{31967321}} gab.com Text Cross-species transmission of the newly identified coronavirus 2019-nCoV JO: J Med Virol http://www.kidney.de/pget.php?&tw=1&pmid=31967321 #FOAvip The current outbreak of viral pneumonia in the city of Wuhan, China, was caused by a novel coronavirus designated 2019-nCoV by the World Health Organization, as determined by sequencing the viral RNA genome. Many initial patients were exposed to wildlife animals at the Huanan seafood wholesale market, where poultry, snake, bats, and other farm animals were also sold. To investigate possible virus reservoir, we have carried out comprehensive sequence analysis and comparison in conjunction with relative synonymous codon usage (RSCU) bias among different animal species based on the 2019-nCoV sequence. Results obtained from our analyses suggest that the 2019-nCoV may appear to be a recombinant virus between the bat coronavirus and an origin-unknown coronavirus. The recombination may occurred within the viral spike glycoprotein, which recognizes a cell surface receptor. Additionally, our findings suggest that 2019-nCoV has most similar genetic information with bat coronovirus and most similar codon usage bias with snake. Taken together, our results suggest that homologous recombination may occur and contribute to the 2019-nCoV cross-species transmission. Twit Text FOAVip Cross-species transmission of the newly identified coronavirus 2019-nCoV ????J Med Virol http://www.kidney.de/pget.php?&tw=1&pmid=31967321 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=31967321 #FOAvip English Wikipedia <ref>{{Cite pmid|31967321}}</ref> Cross-species transmission of the newly identified coronavirus 2019-nCoV #MMPMID31967321 Ji W; Wang W; Zhao X; Zai J; Li X J Med Virol 2020[Apr]; 92 (4): 433-440 PMID31967321show ga The current outbreak of viral pneumonia in the city of Wuhan, China, was caused by a novel coronavirus designated 2019-nCoV by the World Health Organization, as determined by sequencing the viral RNA genome. Many initial patients were exposed to wildlife animals at the Huanan seafood wholesale market, where poultry, snake, bats, and other farm animals were also sold. To investigate possible virus reservoir, we have carried out comprehensive sequence analysis and comparison in conjunction with relative synonymous codon usage (RSCU) bias among different animal species based on the 2019-nCoV sequence. Results obtained from our analyses suggest that the 2019-nCoV may appear to be a recombinant virus between the bat coronavirus and an origin-unknown coronavirus. The recombination may occurred within the viral spike glycoprotein, which recognizes a cell surface receptor. Additionally, our findings suggest that 2019-nCoV has most similar genetic information with bat coronovirus and most similar codon usage bias with snake. Taken together, our results suggest that homologous recombination may occur and contribute to the 2019-nCoV cross-species transmission. |*Disease Reservoirs[MESH] |Animals[MESH] |Betacoronavirus/classification/*genetics/physiology[MESH] |Bungarus/genetics/virology[MESH] |COVID-19[MESH] |Chiroptera/genetics/*virology[MESH] |Codon Usage[MESH] |Coronavirus Infections/epidemiology/*transmission/*virology[MESH] |Disease Outbreaks[MESH] |Evolution, Molecular[MESH] |Genome, Viral[MESH] |Homologous Recombination[MESH] |Host Specificity[MESH] |Humans[MESH] |Naja naja/genetics/virology[MESH] |Phylogeny[MESH] |Pneumonia, Viral/epidemiology/*transmission/*virology[MESH] |SARS-CoV-2[MESH] |Snakes/genetics/*virology[MESH] |Spike Glycoprotein, Coronavirus/*genetics[MESH]Cross-species transmission of the newly identified coronavirus 2019-nC(epmc).pdf DeepDyve Pubget Overpricing