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10.3760/cma.j.cn112148-20200228-00137 http://scihub22266oqcxt.onion/10.3760/cma.j.cn112148-20200228-00137 32171190!ä!32171190 Warning: Undefined variable $yww in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 538 Warning: Undefined variable $yww in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 538 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\32171190.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Zhonghua+Xin+Xue+Guan+Bing+Za+Zhi 2020 ; 48 (6): 456-460 Nephropedia Template TP {{tp|p=32171190|t=2020. Impact of complicated myocardial injury on the clinical outcome of severe or critically ill COVID-19 patients |pdf=|usr=}}{{32171190}} gab.com Text Impact of complicated myocardial injury on the clinical outcome of severe or critically ill COVID-19 patients JO: Zhonghua Xin Xue Guan Bing Za Zhi http://www.kidney.de/pget.php?&tw=1&pmid=32171190 #FOAvip Objective: To analyze the clinical characteristics of the severe or critically ill patients with novel coronavirus pneumonia (COVID-19), and evaluate the impact of complicated myocardial injury on the prognosis of these patients. Methods: A retrospective study was conducted in 54 patients who admitted to Tongji hospital from February 3, 2020 to February 24, 2020 and met the criteria of severe or critical conditions of COVID-19. The clinical characteristics and hospital mortality rate were analyzed and compared between the patients with or without myocardial injury, which was defined with 3 times higher serum cardiac troponin value. Results: The age of the 54 patients was 68.0(59.8, 74.3) years. Among all the patients, 24 (44.4%) patients were complicated with hypertension, 13 (24.1%) with diabetes, 8 (14.8%) with coronary heart disease, and 3 (5.6%) with previous cerebral infarction. During hospitalization, 24 (44.4%) of the patients were complicated with myocardial injury and 26 (48.1%) patients died in hospital. In-hospital mortality was significantly higher in patients with myocardial injury than in patients without myocardial injury (14 (60.9%) vs. 8 (25.8%), P=0.013). Moreover, the levels of C-reactive protein (153.6 (80.3, 240.7) ng/L vs. 49.8 (15.9, 101.9) ng/L) and N-terminal pro-B-type natriuretic peptide (852.0 (400.0, 2 315.3) ng/L vs. 197.0 (115.3, 631.0) ng/L) were significantly higher than patients without myocardial injury (all P<0.01). Conclusions: Prevalence of myocardial injury is high among severe or critically ill COVID-19 patients. Severe or critically ill COVID-19 patients with myocardial injury face a significantly higher risk of in-hospital mortality. The study suggests that it is important to monitor and manage the myocardial injury during hospitalization for severe or critically ill COVID-19 patients. Twit Text FOAVip Impact of complicated myocardial injury on the clinical outcome of severe or critically ill COVID-19 patients ????Zhonghua Xin Xue Guan Bing Za Zhi http://www.kidney.de/pget.php?&tw=1&pmid=32171190 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32171190 #FOAvip English Wikipedia <ref>{{Cite pmid|32171190}}</ref> Impact of complicated myocardial injury on the clinical outcome of severe or critically ill COVID-19 patients #MMPMID32171190 He XW; Lai JS; Cheng J; Wang MW; Liu YJ; Xiao ZC; Xu C; Li SS; Zeng HS Zhonghua Xin Xue Guan Bing Za Zhi 2020[Jun]; 48 (6): 456-460 PMID32171190show ga Objective: To analyze the clinical characteristics of the severe or critically ill patients with novel coronavirus pneumonia (COVID-19), and evaluate the impact of complicated myocardial injury on the prognosis of these patients. Methods: A retrospective study was conducted in 54 patients who admitted to Tongji hospital from February 3, 2020 to February 24, 2020 and met the criteria of severe or critical conditions of COVID-19. The clinical characteristics and hospital mortality rate were analyzed and compared between the patients with or without myocardial injury, which was defined with 3 times higher serum cardiac troponin value. Results: The age of the 54 patients was 68.0(59.8, 74.3) years. Among all the patients, 24 (44.4%) patients were complicated with hypertension, 13 (24.1%) with diabetes, 8 (14.8%) with coronary heart disease, and 3 (5.6%) with previous cerebral infarction. During hospitalization, 24 (44.4%) of the patients were complicated with myocardial injury and 26 (48.1%) patients died in hospital. In-hospital mortality was significantly higher in patients with myocardial injury than in patients without myocardial injury (14 (60.9%) vs. 8 (25.8%), P=0.013). Moreover, the levels of C-reactive protein (153.6 (80.3, 240.7) ng/L vs. 49.8 (15.9, 101.9) ng/L) and N-terminal pro-B-type natriuretic peptide (852.0 (400.0, 2 315.3) ng/L vs. 197.0 (115.3, 631.0) ng/L) were significantly higher than patients without myocardial injury (all P<0.01). Conclusions: Prevalence of myocardial injury is high among severe or critically ill COVID-19 patients. Severe or critically ill COVID-19 patients with myocardial injury face a significantly higher risk of in-hospital mortality. The study suggests that it is important to monitor and manage the myocardial injury during hospitalization for severe or critically ill COVID-19 patients. |*Betacoronavirus[MESH] |*Coronavirus Infections/complications[MESH] |*Critical Illness[MESH] |*Heart Injuries[MESH] |*Pandemics[MESH] |*Pneumonia, Viral/complications[MESH] |Aged[MESH] |COVID-19[MESH] |Humans[MESH] |Middle Aged[MESH] |Retrospective Studies[MESH] Impact of complicated myocardial injury on the clinical outcome of se(epmc).pdf DeepDyve Pubget Overpricing