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10.3390/nu12030789 http://scihub22266oqcxt.onion/10.3390/nu12030789 32192175!7146294!32192175     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=32192175&cmd=llinks): Failed to open stream: HTTP request failed! 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Pathophysiological Role and Therapeutic Implications of Vitamin D in Autoimmunity: Focus on Chronic Autoimmune Diseases |pdf=|usr=}}{{32192175}} gab.com Text Pathophysiological Role and Therapeutic Implications of Vitamin D in Autoimmunity: Focus on Chronic Autoimmune Diseases JO: Nutrients http://www.kidney.de/pget.php?&tw=1&pmid=32192175 #FOAvip Vitamin D is a pleiotropic secosteroid yielding multiple actions in human physiology. Besides the canonical regulatory activity on bone metabolism, several non-classical actions have been described and the ability of vitamin D to partake in the regulation of the immune system is particularly interesting, though far stronger and convincing evidence has been collected in in vitro as compared to in vivo studies. Whether vitamin D is able to regulate at physiological concentrations the human immune system remains unproven to date. Consequently, it is not established if vitamin D status is a factor involved in the pathogenesis of immune-mediated diseases and if cholecalciferol supplementation acts as an adjuvant for autoimmune diseases. The development of autoimmunity is a heterogeneous process, which may involve different organs and systems with a wide range of clinical implications. In the present paper, we reviewed the current evidences regarding vitamin D role in the pathogenesis and management of different autoimmune diseases. Twit Text FOAVip Pathophysiological Role and Therapeutic Implications of Vitamin D in Autoimmunity: Focus on Chronic Autoimmune Diseases ????Nutrients http://www.kidney.de/pget.php?&tw=1&pmid=32192175 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32192175 #FOAvip English Wikipedia <ref>{{Cite pmid|32192175}}</ref> Pathophysiological Role and Therapeutic Implications of Vitamin D in Autoimmunity: Focus on Chronic Autoimmune Diseases #MMPMID32192175 Bellan M; Andreoli L; Mele C; Sainaghi PP; Rigamonti C; Piantoni S; De Benedittis C; Aimaretti G; Pirisi M; Marzullo P Nutrients 2020[Mar]; 12 (3): ä PMID32192175show ga Vitamin D is a pleiotropic secosteroid yielding multiple actions in human physiology. Besides the canonical regulatory activity on bone metabolism, several non-classical actions have been described and the ability of vitamin D to partake in the regulation of the immune system is particularly interesting, though far stronger and convincing evidence has been collected in in vitro as compared to in vivo studies. Whether vitamin D is able to regulate at physiological concentrations the human immune system remains unproven to date. Consequently, it is not established if vitamin D status is a factor involved in the pathogenesis of immune-mediated diseases and if cholecalciferol supplementation acts as an adjuvant for autoimmune diseases. The development of autoimmunity is a heterogeneous process, which may involve different organs and systems with a wide range of clinical implications. In the present paper, we reviewed the current evidences regarding vitamin D role in the pathogenesis and management of different autoimmune diseases. |*Autoimmune Diseases/drug therapy/immunology/pathology[MESH] |*Cholecalciferol/immunology/therapeutic use[MESH] |*Vitamin D Deficiency/drug therapy/immunology/pathology[MESH] |Chronic Disease[MESH]Pathophysiological Role and Therapeutic Implications of Vitamin D in (epmc).pdf DeepDyve Pubget Overpricing