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10.1007/s11739-020-02331-1 http://scihub22266oqcxt.onion/10.1007/s11739-020-02331-1 32297089!7157827!32297089     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=32297089&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\32297089.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Intern+Emerg+Med 2020 ; 15 (5): 751-753 Nephropedia Template TP {{tp|p=32297089|t=2020. Switch from oral anticoagulants to parenteral heparin in SARS-CoV-2 hospitalized patients |pdf=|usr=}}{{32297089}} gab.com Text Switch from oral anticoagulants to parenteral heparin in SARS-CoV-2 hospitalized patients JO: Intern Emerg Med http://www.kidney.de/pget.php?&tw=1&pmid=32297089 #FOAvip The development of COVID-19 syndrome in anticoagulated patients, and especially their admission to intensive-care units with acute severe respiratory syndrome (SARS-CoV-2), expose them to specific problems related to their therapy, in addition to those associated with the acute viral infection. Patients on VKA hospitalized with SARS-CoV-2 show high instability of PT INR due to the variability of vitamin K metabolism, diet, fasting, co-medications, liver impairment, and heart failure. Patients on DOAC are exposed to under/over treatment caused by significant pharmacological interferences. In consideration of the pharmacological characteristics of oral anticoagulant drugs, the multiple pharmacological interactions due to the treatment of acute disease and the possible necessity of mechanical ventilation with hospitalization in intensive-care units, we suggest replacing oral anticoagulant therapies (VKA and DOAC) with parenteral heparin to avoid the risk of over/under treatment. Twit Text FOAVip Switch from oral anticoagulants to parenteral heparin in SARS-CoV-2 hospitalized patients ????Intern Emerg Med http://www.kidney.de/pget.php?&tw=1&pmid=32297089 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32297089 #FOAvip English Wikipedia <ref>{{Cite pmid|32297089}}</ref> Switch from oral anticoagulants to parenteral heparin in SARS-CoV-2 hospitalized patients #MMPMID32297089 Testa S; Paoletti O; Giorgi-Pierfranceschi M; Pan A Intern Emerg Med 2020[Aug]; 15 (5): 751-753 PMID32297089show ga The development of COVID-19 syndrome in anticoagulated patients, and especially their admission to intensive-care units with acute severe respiratory syndrome (SARS-CoV-2), expose them to specific problems related to their therapy, in addition to those associated with the acute viral infection. Patients on VKA hospitalized with SARS-CoV-2 show high instability of PT INR due to the variability of vitamin K metabolism, diet, fasting, co-medications, liver impairment, and heart failure. Patients on DOAC are exposed to under/over treatment caused by significant pharmacological interferences. In consideration of the pharmacological characteristics of oral anticoagulant drugs, the multiple pharmacological interactions due to the treatment of acute disease and the possible necessity of mechanical ventilation with hospitalization in intensive-care units, we suggest replacing oral anticoagulant therapies (VKA and DOAC) with parenteral heparin to avoid the risk of over/under treatment. |Administration, Oral[MESH] |Anticoagulants/*administration & dosage/adverse effects[MESH] |Betacoronavirus[MESH] |COVID-19[MESH] |Coronavirus Infections/*complications[MESH] |Critical Care[MESH] |Drug Interactions[MESH] |Heparin/*administration & dosage/adverse effects[MESH] |Hospitalization[MESH] |Humans[MESH] |Infusions, Parenteral[MESH] |Pandemics[MESH] |Pneumonia, Viral/*complications[MESH]Switch from oral anticoagulants to parenteral heparin in SARS-CoV-2 ho(epmc).pdf DeepDyve Pubget Overpricing