
| 10.1016/j.adro.2020.04.011
http://scihub22266oqcxt.onion/10.1016/j.adro.2020.04.011
 32322758!7175910!32322758
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Adv+Radiat+Oncol 2020 ; 5 (4): 687-689 Nephropedia Template TP
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Management of Locally Advanced Rectal Cancer During The COVID-19 Pandemic: A Necessary Paradigm Change at Memorial Sloan Kettering Cancer Center #MMPMID32322758Romesser PB; Wu AJ; Cercek A; Smith JJ; Weiser M; Saltz L; Garcia-Aguilar J; Crane CHAdv Radiat Oncol 2020[Jul]; 5 (4): 687-689 PMID32322758show ga
The COVID-19 pandemic will consume significant health care resources. Given the concerns for rapidly increasing infection rates in the United States, impending staffing shortages, and the potential for resource reallocation, we rapidly reevaluated our rectal cancer practice policies during this public health emergency. Before the pandemic, we commonly used total neoadjuvant therapy with a strong preference for long-course chemoradiation. In the setting of the ongoing pandemic, we now mandate short-course radiation therapy (SCRT). Despite multiple randomized trials demonstrating no difference in locoregional recurrence, distant recurrence, or overall survival between SCRT and long-course chemoradiation, the adaptation of SCRT in the United States has been low given concerns for less tumor downstaging and increased toxicity. In the setting of the ongoing and likely prolonged COVID-19 pandemic, we feel that these concerns must be reevaluated, because SCRT presents a well-validated alternative that will allow us to meet the needs of a greater number of potentially curable patients at a time when resources are severely and acutely constrained.�
  
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