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Antibody responses to SARS-CoV-2 in patients with COVID-19 #MMPMID32350462
Long QX; Liu BZ; Deng HJ; Wu GC; Deng K; Chen YK; Liao P; Qiu JF; Lin Y; Cai XF; Wang DQ; Hu Y; Ren JH; Tang N; Xu YY; Yu LH; Mo Z; Gong F; Zhang XL; Tian WG; Hu L; Zhang XX; Xiang JL; Du HX; Liu HW; Lang CH; Luo XH; Wu SB; Cui XP; Zhou Z; Zhu MM; Wang J; Xue CJ; Li XF; Wang L; Li ZJ; Wang K; Niu CC; Yang QJ; Tang XJ; Zhang Y; Liu XM; Li JJ; Zhang DC; Zhang F; Liu P; Yuan J; Li Q; Hu JL; Chen J; Huang AL
Nat Med 2020[Jun]; 26 (6): 845-848 PMID32350462show ga
We report acute antibody responses to SARS-CoV-2 in 285 patients with COVID-19. Within 19 days after symptom onset, 100% of patients tested positive for antiviral immunoglobulin-G (IgG). Seroconversion for IgG and IgM occurred simultaneously or sequentially. Both IgG and IgM titers plateaued within 6 days after seroconversion. Serological testing may be helpful for the diagnosis of suspected patients with negative RT-PCR results and for the identification of asymptomatic infections.