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10.4155/tde-2020-0035 http://scihub22266oqcxt.onion/10.4155/tde-2020-0035 32397911!7222554!32397911     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=32397911&cmd=llinks): Failed to open stream: HTTP request failed! 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COVID-19 pandemic: an overview of epidemiology, pathogenesis, diagnostics and potential vaccines and therapeutics |pdf=|usr=}}{{32397911}} gab.com Text COVID-19 pandemic: an overview of epidemiology, pathogenesis, diagnostics and potential vaccines and therapeutics JO: Ther Deliv http://www.kidney.de/pget.php?&tw=1&pmid=32397911 #FOAvip At the time of writing this review, severe acute respiratory coronavirus syndrome-2 (SARS-CoV-2) has infected more than 2,355,853 patients and resulted in more than 164,656 deaths worldwide (as of 20 April 2020). This review highlights the preventive measures, available clinical therapies and the potential of vaccine development against SARS-CoV-2 by taking into consideration the strong genetic similarities of the 2003 epidemic SARS-CoV. Recent studies are investigating the repurposing of US FDA-approved drugs as there is no available vaccine yet with many attempts under clinical evaluation. Several antivirals, antimalarials and immunomodulators that have shown activity against SARS-CoV and Middle East coronavirus respiratory syndromes are being evaluated. In particular, hydroxychloroquine, remdesivir, favipiravir, arbidol, tocilizumab and bevacizumab have shown promising results. The main aim of this review is to provide an overview of this pandemic and where we currently stand. Twit Text FOAVip COVID-19 pandemic: an overview of epidemiology, pathogenesis, diagnostics and potential vaccines and therapeutics ????Ther Deliv http://www.kidney.de/pget.php?&tw=1&pmid=32397911 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32397911 #FOAvip English Wikipedia <ref>{{Cite pmid|32397911}}</ref> COVID-19 pandemic: an overview of epidemiology, pathogenesis, diagnostics and potential vaccines and therapeutics #MMPMID32397911 Amawi H; Abu Deiab GI; A Aljabali AA; Dua K; Tambuwala MM Ther Deliv 2020[Apr]; 11 (4): 245-268 PMID32397911show ga At the time of writing this review, severe acute respiratory coronavirus syndrome-2 (SARS-CoV-2) has infected more than 2,355,853 patients and resulted in more than 164,656 deaths worldwide (as of 20 April 2020). This review highlights the preventive measures, available clinical therapies and the potential of vaccine development against SARS-CoV-2 by taking into consideration the strong genetic similarities of the 2003 epidemic SARS-CoV. Recent studies are investigating the repurposing of US FDA-approved drugs as there is no available vaccine yet with many attempts under clinical evaluation. Several antivirals, antimalarials and immunomodulators that have shown activity against SARS-CoV and Middle East coronavirus respiratory syndromes are being evaluated. In particular, hydroxychloroquine, remdesivir, favipiravir, arbidol, tocilizumab and bevacizumab have shown promising results. The main aim of this review is to provide an overview of this pandemic and where we currently stand. |*Betacoronavirus/genetics[MESH] |*Coronavirus Infections/diagnosis/drug therapy/epidemiology/genetics/immunology/prevention & control/therapy[MESH] |*Pandemics/prevention & control[MESH] |*Pneumonia, Viral/diagnosis/epidemiology/prevention & control/therapy[MESH] |*Viral Vaccines/genetics/immunology[MESH] |Antiviral Agents/therapeutic use[MESH] |COVID-19[MESH] |COVID-19 Drug Treatment[MESH] |COVID-19 Testing[MESH] |COVID-19 Vaccines[MESH] |Clinical Laboratory Techniques[MESH] |Coronavirus/genetics[MESH] |Disease Progression[MESH] |Humans[MESH] |RNA, Viral[MESH]COVID-19 pandemic: an overview of epidemiology, pathogenesis, diagnost(epmc).pdf DeepDyve Pubget Overpricing