
| 10.1016/j.ando.2020.05.001
http://scihub22266oqcxt.onion/10.1016/j.ando.2020.05.001
 32413342!7217100!32413342
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Ann+Endocrinol+(Paris) 2020 ; 81 (2-3): 101-109 Nephropedia Template TP
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COVID-19 in diabetic patients: Related risks and specifics of management #MMPMID32413342Orioli L; Hermans MP; Thissen JP; Maiter D; Vandeleene B; Yombi JCAnn Endocrinol (Paris) 2020[Jun]; 81 (2-3): 101-109 PMID32413342show ga
Diabetes is among the most frequently reported comorbidities in patients infected with COVID-19. According to current data, diabetic patients do not appear to be at increased risk of contracting SARS-CoV-2 compared to the general population. On the other hand, diabetes is a risk factor for developing severe and critical forms of COVID-19, the latter requiring admission to an intensive care unit and/or use of invasive mechanical ventilation, with high mortality rates. The characteristics of diabetic patients at risk for developing severe and critical forms of COVID-19, as well as the prognostic impact of diabetes on the course of COVID-19, are under current investigation. Obesity, the main risk factor for incident type 2 diabetes, is more common in patients with critical forms of COVID-19 requiring invasive mechanical ventilation. On the other hand, COVID-19 is usually associated with poor glycemic control and a higher risk of ketoacidosis in diabetic patients. There are currently no recommendations in favour of discontinuing antihypertensive medications that interact with the renin-angiotensin-aldosterone system. Metformin and SGLT2 inhibitors should be discontinued in patients with severe forms of COVID-19 owing to the risks of lactic acidosis and ketoacidosis. Finally, we advise for systematic screening for (pre)diabetes in patients with proven COVID-19 infection.|Acidosis, Lactic/chemically induced/epidemiology/virology[MESH]|Betacoronavirus/physiology[MESH]|COVID-19[MESH]|Comorbidity[MESH]|Coronavirus Infections/*complications/diagnosis/epidemiology/*therapy[MESH]|Critical Illness/epidemiology/therapy[MESH]|Diabetes Mellitus, Type 2/*complications/diagnosis/epidemiology/*therapy[MESH]|Diabetic Ketoacidosis/chemically induced/epidemiology/virology[MESH]|Humans[MESH]|Mass Screening/methods/standards[MESH]|Metformin/therapeutic use[MESH]|Obesity/complications/epidemiology/therapy[MESH]|Pandemics[MESH]|Pneumonia, Viral/*complications/diagnosis/epidemiology/*therapy[MESH]|Prediabetic State/complications/diagnosis/epidemiology/therapy[MESH]|Renin-Angiotensin System/physiology[MESH]|Risk Factors[MESH]|Risk Management[MESH]|SARS-CoV-2[MESH]|Severity of Illness Index[MESH]|Sodium-Glucose Transporter 2 Inhibitors/therapeutic use[MESH]
  
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