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10.1007/s11739-020-02383-3 http://scihub22266oqcxt.onion/10.1007/s11739-020-02383-3 32458206!7249615!32458206     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=32458206&cmd=llinks): Failed to open stream: HTTP request failed! 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Potential new treatment strategies for COVID-19: is there a role for bromhexine as add-on therapy?|pdf=|usr=}}{{32458206}} gab.com Text Potential new treatment strategies for COVID-19: is there a role for bromhexine as add-on therapy JO: Intern Emerg Med http://www.kidney.de/pget.php?&tw=1&pmid=32458206 #FOAvip Of huge importance now is to provide a fast, cost-effective, safe, and immediately available pharmaceutical solution to curb the rapid global spread of SARS-CoV-2. Recent publications on SARS-CoV-2 have brought attention to the possible benefit of chloroquine in the treatment of patients infected by SARS-CoV-2. Whether chloroquine can treat SARS-CoV-2 alone and also work as a prophylactic is doubtful. An effective prophylactic medication to prevent viral entry has to contain, at least, either a protease inhibitor or a competitive virus ACE2-binding inhibitor. Using bromhexine at a dosage that selectively inhibits TMPRSS2 and, in so doing, inhibits TMPRSS2-specific viral entry is likely to be effective against SARS-CoV-2. We propose the use of bromhexine as a prophylactic and treatment. We encourage the scientific community to assess bromhexine clinically as a prophylactic and curative treatment. If proven to be effective, this would allow a rapid, accessible, and cost-effective application worldwide. Twit Text FOAVip Potential new treatment strategies for COVID-19: is there a role for bromhexine as add-on therapy ????Intern Emerg Med http://www.kidney.de/pget.php?&tw=1&pmid=32458206 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32458206 #FOAvip English Wikipedia <ref>{{Cite pmid|32458206}}</ref> Potential new treatment strategies for COVID-19: is there a role for bromhexine as add-on therapy? #MMPMID32458206 Depfenhart M; de Villiers D; Lemperle G; Meyer M; Di Somma S Intern Emerg Med 2020[Aug]; 15 (5): 801-812 PMID32458206show ga Of huge importance now is to provide a fast, cost-effective, safe, and immediately available pharmaceutical solution to curb the rapid global spread of SARS-CoV-2. Recent publications on SARS-CoV-2 have brought attention to the possible benefit of chloroquine in the treatment of patients infected by SARS-CoV-2. Whether chloroquine can treat SARS-CoV-2 alone and also work as a prophylactic is doubtful. An effective prophylactic medication to prevent viral entry has to contain, at least, either a protease inhibitor or a competitive virus ACE2-binding inhibitor. Using bromhexine at a dosage that selectively inhibits TMPRSS2 and, in so doing, inhibits TMPRSS2-specific viral entry is likely to be effective against SARS-CoV-2. We propose the use of bromhexine as a prophylactic and treatment. We encourage the scientific community to assess bromhexine clinically as a prophylactic and curative treatment. If proven to be effective, this would allow a rapid, accessible, and cost-effective application worldwide. |Betacoronavirus[MESH] |Bromhexine/*therapeutic use[MESH] |COVID-19[MESH] |Coronavirus Infections/*drug therapy[MESH] |Expectorants/*therapeutic use[MESH] |Humans[MESH] |Pandemics[MESH] |Pneumonia, Viral/*drug therapy[MESH] |SARS-CoV-2[MESH] |Serine Endopeptidases/*drug effects[MESH]Potential new treatment strategies for COVID-19: is there a role for b(epmc).pdf DeepDyve Pubget Overpricing