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Indian+J+Public+Health 2020 ; 64 (Supplement): S112-S116 Nephropedia Template TP
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Potential pharmacological agents for COVID-19 #MMPMID32496239Kotwani A; Gandra SIndian J Public Health 2020[Jun]; 64 (Supplement): S112-S116 PMID32496239show ga
A novel coronavirus disease 2019 (COVID-19) infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) first emerged in December 2019 in Wuhan, China, has become a global pandemic. Currently, the management of COVID-19 infection is mainly supportive. Several clinical trials worldwide are evaluating several drugs approved for other indications, as well as multiple investigational agents for the treatment and prevention of COVID-19. Here, we give a brief overview of pharmacological agents and other therapies which are under investigation as treatment options or adjunctive agents for patients infected with COVID-19 and for chemoprophylaxis for the prevention of COVID-19 infection. At the time of writing this commentary, there is no peer-reviewed published evidence from randomized clinical trials of any pharmacological agents improving outcomes in COVID-19 patients. However, it was reported that remdesivir an investigational antiviral agent hastens clinical recovery, but a study is yet to be published in peer-reviewed medical journal.|Antimalarials/therapeutic use[MESH]|Antiviral Agents/adverse effects/pharmacology/*therapeutic use[MESH]|Betacoronavirus[MESH]|COVID-19[MESH]|COVID-19 Serotherapy[MESH]|Clinical Trials as Topic[MESH]|Coronavirus[MESH]|Coronavirus Infections/*drug therapy/therapy[MESH]|Humans[MESH]|Immunization, Passive[MESH]|Immunoglobulins/therapeutic use[MESH]|Interleukins/antagonists & inhibitors[MESH]|Pandemics[MESH]|Pneumonia, Viral/*drug therapy/therapy[MESH]
  
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